On this page, we present all of the funds holding AGIO from our database of 13F filers, detailed in the table below. The first column indicates the name of each of the funds holding AGIO, with a link to that fund's top holdings. The next columns indicate the amount of AGIO stock held by each of the funds holding AGIO, followed by the AGIO position size held by the fund, and lastly the date of the quarterly filing period the data represents. In total, we count 172 funds holding AGIO within the last two filing periods in our coverage universe of 13F filers, with the largest position size having been reported by Vanguard Group Inc.. For more details on the positions held by Vanguard Group Inc. (or by any of the other funds holding AGIO), click the fund name in the "Holder" column of the funds-holding-AGIO table below.

Holder	Amount	Position Size ($ in 1000's)	As of
Vanguard Group Inc.	5,527,438	$123,096	12/31/2023
AGIO	5,527,438	$123,096	12/31/2023
BlackRock Inc.	4,962,237	$110,509	12/31/2023
AGIO	4,962,237	$110,509	12/31/2023
Farallon Capital Management LLC	4,167,602	$92,812	12/31/2023
AGIO	4,167,602	$92,812	12/31/2023
Bellevue Group AG	4,011,000	$89,325	12/31/2023
AGIO	4,011,000	$89,325	12/31/2023
Armistice Capital LLC	3,524,000	$78,479	12/31/2023
AGIO	3,524,000	$78,479	12/31/2023
State Street Corp	2,625,685	$58,474	12/31/2023
AGIO	2,625,685	$58,474	12/31/2023
Dimensional Fund Advisors LP	2,596,764	$57,832	12/31/2023
AGIO	2,596,764	$57,832	12/31/2023
JPMorgan Chase & Co.	2,542,746	$56,627	12/31/2023
AGIO	2,542,746	$56,627	12/31/2023
Rock Springs Capital Management LP	2,152,173	$47,929	12/31/2023
AGIO	2,152,173	$47,929	12/31/2023
Macquarie Group Ltd.	2,015,414	$44,883	12/31/2023
AGIO	2,015,414	$44,883	12/31/2023
First Trust Advisors LP	1,818,643	$40,501	12/31/2023
AGIO	1,818,643	$40,501	12/31/2023
Price T Rowe Associates Inc. MD	1,624,612	$36,181	12/31/2023
AGIO	1,624,612	$36,181	12/31/2023
ArrowMark Colorado Holdings LLC	1,553,882	$34,605	12/31/2023
AGIO	1,553,882	$34,605	12/31/2023
Geode Capital Management LLC	1,254,277	$27,936	12/31/2023
AGIO	1,254,277	$27,936	12/31/2023
Citadel Advisors LLC		$24,069	12/31/2023
AGIO	1,074,812	$23,936	12/31/2023
Call	11,200	$249	12/31/2023
Put	5,200	$116	12/31/2023
Deep Track Capital LP	1,062,881	$23,670	12/31/2023
AGIO	1,062,881	$23,670	12/31/2023
BNP PARIBAS ASSET MANAGEMENT Holding S.A.	1,046,460	$23,305	12/31/2023
AGIO	1,046,460	$23,305	12/31/2023
Pictet Asset Management Holding SA	958,280	$21,341	12/31/2023
AGIO	958,280	$21,341	12/31/2023
T. Rowe Price Investment Management Inc.	929,906	$20,710	12/31/2023
AGIO	929,906	$20,710	12/31/2023
Fisher Asset Management LLC	711,521	$15,846	12/31/2023
AGIO	711,521	$15,846	12/31/2023
Northern Trust Corp	620,239	$13,813	12/31/2023
AGIO	620,239	$13,813	12/31/2023
Goldman Sachs Group Inc.	607,938	$13,539	12/31/2023
AGIO	607,938	$13,539	12/31/2023
Assenagon Asset Management S.A.	454,801	$13,298	03/31/2024
AGIO	454,801	$13,298	03/31/2024
Deutsche Bank AG	581,299	$12,946	12/31/2023
AGIO	581,299	$12,946	12/31/2023
Frazier Life Sciences Management L.P.	523,166	$11,651	12/31/2023
AGIO	523,166	$11,651	12/31/2023
Morgan Stanley	493,587	$10,992	12/31/2023
AGIO	493,587	$10,992	12/31/2023
Hudson Bay Capital Management LP	490,000	$10,912	12/31/2023
AGIO	490,000	$10,912	12/31/2023
Charles Schwab Investment Management Inc.	456,394	$10,164	12/31/2023
AGIO	456,394	$10,164	12/31/2023
Caligan Partners LP	441,833	$9,840	12/31/2023
AGIO	441,833	$9,840	12/31/2023
Suvretta Capital Management LLC	399,451	$8,896	12/31/2023
AGIO	399,451	$8,896	12/31/2023
Nordea Investment Management AB	266,588	$7,824	03/31/2024
AGIO	266,588	$7,824	03/31/2024
Walleye Capital LLC		$7,547	12/31/2023
AGIO	336,462	$7,493	12/31/2023
Call	5,100	$114	12/31/2023
Put	2,700	$60	12/31/2023
Eagle Health Investments LP	330,830	$7,368	12/31/2023
AGIO	330,830	$7,368	12/31/2023
Norges Bank	306,526	$6,826	12/31/2023
AGIO	306,526	$6,826	12/31/2023
Boothbay Fund Management LLC	286,445	$6,379	12/31/2023
AGIO	286,445	$6,379	12/31/2023
AXA S.A.	265,299	$5,908	12/31/2023
AGIO	265,299	$5,908	12/31/2023
Bank of New York Mellon Corp	195,958	$5,730	03/31/2024
AGIO	195,958	$5,730	03/31/2024
D. E. Shaw & Co. Inc.	216,484	$4,821	12/31/2023
AGIO	216,484	$4,821	12/31/2023
Bank of America Corp DE	205,954	$4,587	12/31/2023
AGIO	205,954	$4,587	12/31/2023
Man Group plc	180,428	$4,018	12/31/2023
AGIO	180,428	$4,018	12/31/2023
Nuveen Asset Management LLC	156,106	$3,476	12/31/2023
AGIO	156,106	$3,476	12/31/2023
Barclays PLC		$3,446	12/31/2023
AGIO	154,736	$3,446	12/31/2023
Put	60,000	$1,336	12/31/2023
Call	60,000	$1,336	12/31/2023
Rafferty Asset Management LLC	153,485	$3,418	12/31/2023
AGIO	153,485	$3,418	12/31/2023
Allianz Asset Management GmbH	149,111	$3,321	12/31/2023
AGIO	149,111	$3,321	12/31/2023
Voya Investment Management LLC	138,163	$3,077	12/31/2023
AGIO	138,163	$3,077	12/31/2023
UBS Oconnor LLC	126,819	$2,824	12/31/2023
AGIO	126,819	$2,824	12/31/2023
Qube Research & Technologies Ltd	117,512	$2,617	12/31/2023
AGIO	117,512	$2,617	12/31/2023
State of New Jersey Common Pension Fund D	84,822	$2,480	03/31/2024
AGIO	84,822	$2,480	03/31/2024
Swiss National Bank	109,860	$2,447	12/31/2023
AGIO	109,860	$2,447	12/31/2023
Credit Suisse AG	109,194	$2,432	12/31/2023
AGIO	109,194	$2,432	12/31/2023
Susquehanna International Group LLP		$2,415	12/31/2023
Call	85,900	$1,913	12/31/2023
AGIO	22,530	$502	12/31/2023
Citigroup Inc.		$2,388	12/31/2023
AGIO	107,228	$2,388	12/31/2023
Put	28,800	$641	12/31/2023
Call	28,800	$641	12/31/2023
ExodusPoint Capital Management LP	101,114	$2,252	12/31/2023
AGIO	101,114	$2,252	12/31/2023
Rhumbline Advisers	100,498	$2,238	12/31/2023
AGIO	100,498	$2,238	12/31/2023
TD Asset Management Inc.	92,218	$2,054	12/31/2023
AGIO	92,218	$2,054	12/31/2023
PDT Partners LLC	85,153	$1,896	12/31/2023
AGIO	85,153	$1,896	12/31/2023
Invesco Ltd.	80,089	$1,784	12/31/2023
AGIO	80,089	$1,784	12/31/2023
Alliancebernstein L.P.	73,582	$1,639	12/31/2023
AGIO	73,582	$1,639	12/31/2023
Ameriprise Financial Inc.	72,926	$1,624	12/31/2023
AGIO	72,926	$1,624	12/31/2023
Prudential Financial Inc.	69,532	$1,548	12/31/2023
AGIO	69,532	$1,548	12/31/2023
American Century Companies Inc.	62,352	$1,389	12/31/2023
AGIO	62,352	$1,389	12/31/2023
Skandinaviska Enskilda Banken AB publ	62,360	$1,388	12/31/2023
AGIO	62,360	$1,388	12/31/2023
California State Teachers Retirement System	58,784	$1,309	12/31/2023
AGIO	58,784	$1,309	12/31/2023
Royal Bank of Canada	56,544	$1,259	12/31/2023
AGIO	56,544	$1,259	12/31/2023
Legal & General Group Plc	54,981	$1,224	12/31/2023
AGIO	54,981	$1,224	12/31/2023
Trexquant Investment LP	54,541	$1,215	12/31/2023
AGIO	54,541	$1,215	12/31/2023
Oak Ridge Investments LLC	40,043	$1,171	03/31/2024
AGIO	40,043	$1,171	03/31/2024
Jane Street Group LLC		$1,156	12/31/2023
AGIO	98,021	$2,183	12/31/2023
Put	46,100	$1,027	12/31/2023
DekaBank Deutsche Girozentrale	40,000	$1,149	03/31/2024
AGIO	40,000	$1,149	03/31/2024
Mirae Asset Global Investments Co. Ltd.	39,248	$1,148	03/31/2024
AGIO	39,248	$1,148	03/31/2024
The Manufacturers Life Insurance Company	49,678	$1,106	12/31/2023
AGIO	49,678	$1,106	12/31/2023
UBS Asset Management Americas Inc.	47,461	$1,057	12/31/2023
AGIO	47,461	$1,057	12/31/2023
Two Sigma Investments LP	45,923	$1,023	12/31/2023
AGIO	45,923	$1,023	12/31/2023
Wellington Management Group LLP	45,467	$1,013	12/31/2023
AGIO	45,467	$1,013	12/31/2023
Orbimed Advisors LLC	45,000	$1,002	12/31/2023
AGIO	45,000	$1,002	12/31/2023
Millennium Management LLC	44,359	$988	12/31/2023
AGIO	44,359	$988	12/31/2023
Martingale Asset Management L P	43,310	$965	12/31/2023
AGIO	43,310	$965	12/31/2023
Renaissance Technologies LLC	42,714	$951	12/31/2023
AGIO	42,714	$951	12/31/2023
Campbell & CO Investment Adviser LLC	42,686	$951	12/31/2023
AGIO	42,686	$951	12/31/2023
Balyasny Asset Management LLC	42,003	$935	12/31/2023
AGIO	42,003	$935	12/31/2023
State of Wisconsin Investment Board	41,552	$925	12/31/2023
AGIO	41,552	$925	12/31/2023
BNP Paribas Arbitrage SA	31,575	$923	03/31/2024
AGIO	31,575	$923	03/31/2024
Simplex Trading LLC		$903	03/31/2024
Call	33,300	$973	03/31/2024
Put	2,400	$70	03/31/2024
GSA Capital Partners LLP	30,853	$902	03/31/2024
AGIO	30,853	$902	03/31/2024
Alps Advisors Inc.	37,844	$843	12/31/2023
AGIO	37,844	$843	12/31/2023
Allen Investment Management LLC	36,166	$805	12/31/2023
AGIO	36,166	$805	12/31/2023
Squarepoint Ops LLC	33,926	$756	12/31/2023
AGIO	33,926	$756	12/31/2023
Ensign Peak Advisors Inc	33,530	$747	12/31/2023
AGIO	33,530	$747	12/31/2023
Great West Life Assurance Co. Can	30,604	$677	12/31/2023
AGIO	30,604	$677	12/31/2023
Edgewood Management LLC	30,000	$668	12/31/2023
AGIO	30,000	$668	12/31/2023
Janus Henderson Group PLC	29,574	$659	12/31/2023
AGIO	29,574	$659	12/31/2023
MetLife Investment Management LLC	29,063	$647	12/31/2023
AGIO	29,063	$647	12/31/2023
Tudor Investment Corp Et Al	27,898	$621	12/31/2023
AGIO	27,898	$621	12/31/2023
Point72 Middle East FZE	27,754	$618	12/31/2023
AGIO	27,754	$618	12/31/2023
American International Group Inc.	27,610	$615	12/31/2023
AGIO	27,610	$615	12/31/2023
Thrivent Financial for Lutherans	25,654	$572	12/31/2023
AGIO	25,654	$572	12/31/2023
Profund Advisors LLC	25,558	$569	12/31/2023
AGIO	25,558	$569	12/31/2023
Engineers Gate Manager LP	24,586	$548	12/31/2023
AGIO	24,586	$548	12/31/2023
Schroder Investment Management Group	24,000	$534	12/31/2023
AGIO	24,000	$534	12/31/2023
Nebula Research & Development LLC	23,338	$520	12/31/2023
AGIO	23,338	$520	12/31/2023
New York State Common Retirement Fund	22,681	$505	12/31/2023
AGIO	22,681	$505	12/31/2023
Brevan Howard Capital Management LP	18,544	$413	12/31/2023
AGIO	18,544	$413	12/31/2023
Principal Financial Group Inc.	13,431	$393	03/31/2024
AGIO	13,431	$393	03/31/2024
CWM Advisors LLC	17,213	$383	12/31/2023
AGIO	17,213	$383	12/31/2023
Walleye Trading LLC		$382	12/31/2023
AGIO	20,321	$453	12/31/2023
Put	3,200	$71	12/31/2023
Teacher Retirement System of Texas	12,438	$364	03/31/2024
AGIO	12,438	$364	03/31/2024
Jump Financial LLC	16,240	$362	12/31/2023
AGIO	16,240	$362	12/31/2023
Envestnet Asset Management Inc.	16,115	$359	12/31/2023
AGIO	16,115	$359	12/31/2023
State Board of Administration of Florida Retirement System	15,847	$353	12/31/2023
AGIO	15,847	$353	12/31/2023
Arizona State Retirement System	15,582	$347	12/31/2023
AGIO	15,582	$347	12/31/2023
Pennant Investors LP	15,100	$336	12/31/2023
AGIO	15,100	$336	12/31/2023
Zurcher Kantonalbank Zurich Cantonalbank	11,444	$335	03/31/2024
AGIO	11,444	$335	03/31/2024
China Universal Asset Management Co. Ltd.	10,780	$315	03/31/2024
AGIO	10,780	$315	03/31/2024
Virtus ETF Advisers LLC	14,036	$313	12/31/2023
AGIO	14,036	$313	12/31/2023
J. Goldman & Co LP		$301	12/31/2023
Call	13,500	$301	12/31/2023
ProShare Advisors LLC	12,765	$284	12/31/2023
AGIO	12,765	$284	12/31/2023
Tower Research Capital LLC TRC	12,479	$278	12/31/2023
AGIO	12,479	$278	12/31/2023
Handelsbanken Fonder AB	12,023	$268	12/31/2023
AGIO	12,023	$268	12/31/2023
Federated Hermes Inc.	11,067	$246	12/31/2023
AGIO	11,067	$246	12/31/2023
Bayesian Capital Management LP	10,800	$241	12/31/2023
AGIO	10,800	$241	12/31/2023
Public Employees Retirement Association of Colorado	10,691	$238	12/31/2023
AGIO	10,691	$238	12/31/2023
Wells Fargo & Company MN		$229	12/31/2023
AGIO	128,383	$2,859	12/31/2023
Put	118,100	$2,630	12/31/2023
Connor Clark & Lunn Investment Management Ltd.	10,131	$226	12/31/2023
AGIO	10,131	$226	12/31/2023
Victory Capital Management Inc.	7,210	$211	03/31/2024
AGIO	7,210	$211	03/31/2024
NEOS Investment Management LLC	9,438	$210	12/31/2023
AGIO	9,438	$210	12/31/2023
XTX Topco Ltd	9,013	$201	12/31/2023
AGIO	9,013	$201	12/31/2023
Headlands Technologies LLC	8,893	$198	12/31/2023
AGIO	8,893	$198	12/31/2023
Cutler Group LP		$194	03/31/2024
AGIO	7,130	$208	03/31/2024
Put	4,200	$14	03/31/2024
Propel Bio Management LLC	5,792	$129	12/31/2023
AGIO	5,792	$129	12/31/2023
Ameritas Investment Partners Inc.	5,519	$123	12/31/2023
AGIO	5,519	$123	12/31/2023
FMR LLC	4,600	$102	12/31/2023
AGIO	4,600	$102	12/31/2023
Cubist Systematic Strategies LLC	4,067	$91	12/31/2023
AGIO	4,067	$91	12/31/2023
EntryPoint Capital LLC	3,461	$77	12/31/2023
AGIO	3,461	$77	12/31/2023
Metropolitan Life Insurance Co NY	3,373	$75	12/31/2023
AGIO	3,373	$75	12/31/2023
Amalgamated Bank	1,867	$55	03/31/2024
AGIO	1,867	$55	03/31/2024
UBS Group AG	1,854	$41	12/31/2023
AGIO	1,854	$41	12/31/2023
Quest Partners LLC	1,863	$41	12/31/2023
AGIO	1,863	$41	12/31/2023
US Bancorp DE	1,108	$25	12/31/2023
AGIO	1,108	$25	12/31/2023
Nisa Investment Advisors LLC	791	$23	03/31/2024
AGIO	791	$23	03/31/2024
Allspring Global Investments Holdings LLC	651	$19	03/31/2024
AGIO	651	$19	03/31/2024
First Horizon Advisors Inc.	588	$17	03/31/2024
AGIO	588	$17	03/31/2024
Signaturefd LLC	493	$14	03/31/2024
AGIO	493	$14	03/31/2024
Russell Investments Group Ltd.	604	$13	12/31/2023
AGIO	604	$13	12/31/2023
The PNC Financial Services Group Inc.	464	$10	12/31/2023
AGIO	464	$10	12/31/2023
NBC Securities Inc.	290	$8	03/31/2024
AGIO	290	$8	03/31/2024
Aspect Partners LLC	361	$8	12/31/2023
AGIO	361	$8	12/31/2023
Spire Wealth Management	230	$7	03/31/2024
AGIO	230	$7	03/31/2024
Daiwa Securities Group Inc.	204	$6	03/31/2024
AGIO	204	$6	03/31/2024
Concord Wealth Partners	200	$6	03/31/2024
AGIO	200	$6	03/31/2024
Valley National Advisers Inc.	157	$5	03/31/2024
AGIO	157	$5	03/31/2024
CWM LLC	169	$5	03/31/2024
AGIO	169	$5	03/31/2024
Bell Investment Advisors Inc	237	$5	12/31/2023
AGIO	237	$5	12/31/2023
North Star Investment Management Corp.	125	$4	03/31/2024
AGIO	125	$4	03/31/2024
Lindbrook Capital LLC	147	$4	03/31/2024
AGIO	147	$4	03/31/2024
Allworth Financial LP	60	$2	03/31/2024
AGIO	60	$2	03/31/2024
Park Place Capital Corp	72	$2	03/31/2024
AGIO	72	$2	03/31/2024
Private Wealth Management Group LLC	84	$2	03/31/2024
AGIO	84	$2	03/31/2024
Quadrant Capital Group LLC	86	$2	12/31/2023
AGIO	86	$2	12/31/2023
Advisor Group Holdings Inc.	103	$2	12/31/2023
AGIO	103	$2	12/31/2023
Riggs Asset Managment Co. Inc.	41	$1	03/31/2024
AGIO	41	$1	03/31/2024
SYSTM Wealth Solutions LLC	35	$1	03/31/2024
AGIO	35	$1	03/31/2024
GAMMA Investing LLC	48	$1	03/31/2024
AGIO	48	$1	03/31/2024
Comerica Bank	67	$1	12/31/2023
AGIO	67	$1	12/31/2023
EverSource Wealth Advisors LLC	59	$1	12/31/2023
AGIO	59	$1	12/31/2023
Farther Finance Advisors LLC	47	$1	12/31/2023
AGIO	47	$1	12/31/2023
Proequities Inc.		$0	03/31/2024
Put	0	$0	03/31/2024
AGIO	0	$0	03/31/2024
Call	0	$0	03/31/2024
JFS Wealth Advisors LLC	4	$0	03/31/2024
AGIO	4	$0	03/31/2024
Nelson Van Denburg & Campbell Wealth Management Group LLC	11	$0	03/31/2024
AGIO	11	$0	03/31/2024
SJS Investment Consulting Inc.	3	$0	03/31/2024
AGIO	3	$0	03/31/2024
Principal Securities Inc.	10	$0	12/31/2023
AGIO	10	$0	12/31/2023
Steward Partners Investment Advisory LLC	9	$0	12/31/2023
AGIO	9	$0	12/31/2023
Covestor Ltd	11	$0	12/31/2023
AGIO	11	$0	12/31/2023
Group One Trading L.P.	1,035	$-2	12/31/2023
Put	3,000	$67	12/31/2023
Call	1,900	$42	12/31/2023
AGIO	1,035	$23	12/31/2023

See Summary: Institutional Holders of AGIO
See Details: Top 10 Hedge Funds Holding AGIO
Also See: AGIO Insider Buying
Also See: AGIO Holdings Changes

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AGIO — Performance