There is a long list of 1456 institutional holders of VRTX within the last two holding periods in our database of 13F filers, so we've sorted through to present to you just the top 50 institutional holders of VRTX by largest to smallest position reported in the institutional investor's latest 13F filing. In the institutional-holders-of-VRTX table below, the initial column indicates the name of each top institutional holder of VRTX, with a link to that fund's top holdings. The next columns indicate the amount of VRTX stock held by each of the institutional holders of VRTX, followed by the VRTX position size held by the institution, and finally the date of the quarterly 13F filing period the holdings data represents for that institution.

Holder	Amount	Position Size ($ in 1000's)	As of
Vanguard Group Inc.	22,282,180	$9,066,396	12/31/2023
VRTX	22,282,180	$9,066,396	12/31/2023
BlackRock Inc.	21,881,203	$8,903,243	12/31/2023
VRTX	21,881,203	$8,903,243	12/31/2023
Capital World Investors	21,805,770	$8,872,586	12/31/2023
VRTX	21,805,770	$8,872,586	12/31/2023
FMR LLC	12,979,511	$5,281,233	12/31/2023
VRTX	12,979,511	$5,281,233	12/31/2023
State Street Corp	12,083,818	$4,916,785	12/31/2023
VRTX	12,083,818	$4,916,785	12/31/2023
Alliancebernstein L.P.	7,039,738	$2,864,399	12/31/2023
VRTX	7,039,738	$2,864,399	12/31/2023
Price T Rowe Associates Inc. MD	5,887,412	$2,395,530	12/31/2023
VRTX	5,887,412	$2,395,530	12/31/2023
Geode Capital Management LLC	5,673,419	$2,302,799	12/31/2023
VRTX	5,673,419	$2,302,799	12/31/2023
JPMorgan Chase & Co.		$2,273,728	12/31/2023
VRTX	5,624,265	$2,288,457	12/31/2023
Put	82,200	$33,446	12/31/2023
Call	46,000	$18,717	12/31/2023
Wellington Management Group LLP	5,228,538	$2,127,440	12/31/2023
VRTX	5,228,538	$2,127,440	12/31/2023
Jennison Associates LLC	3,944,913	$1,605,146	12/31/2023
VRTX	3,944,913	$1,605,146	12/31/2023
Massachusetts Financial Services Co. MA	3,625,802	$1,475,303	12/31/2023
VRTX	3,625,802	$1,475,303	12/31/2023
Capital Research Global Investors	3,567,664	$1,451,647	12/31/2023
VRTX	3,567,664	$1,451,647	12/31/2023
Loomis Sayles & Co. L P	3,134,852	$1,275,540	12/31/2023
VRTX	3,134,852	$1,275,540	12/31/2023
Norges Bank	3,042,288	$1,237,877	12/31/2023
VRTX	3,042,288	$1,237,877	12/31/2023
Morgan Stanley	2,980,455	$1,212,719	12/31/2023
VRTX	2,980,455	$1,212,719	12/31/2023
Amundi	2,718,117	$1,143,825	12/31/2023
VRTX	2,718,117	$1,143,825	12/31/2023
Northern Trust Corp	2,680,597	$1,090,708	12/31/2023
VRTX	2,680,597	$1,090,708	12/31/2023
UBS Asset Management Americas Inc.	2,599,904	$1,057,875	12/31/2023
VRTX	2,599,904	$1,057,875	12/31/2023
Clearbridge Investments LLC	2,592,575	$1,054,893	12/31/2023
VRTX	2,592,575	$1,054,893	12/31/2023
Ameriprise Financial Inc.	2,510,029	$1,021,332	12/31/2023
VRTX	2,510,029	$1,021,332	12/31/2023
Bank of America Corp DE		$995,911	12/31/2023
VRTX	2,435,920	$991,151	12/31/2023
Call	118,600	$48,257	12/31/2023
Put	106,900	$43,497	12/31/2023
Legal & General Group Plc	2,430,665	$989,013	12/31/2023
VRTX	2,430,665	$989,013	12/31/2023
Janus Henderson Group PLC	2,339,979	$952,135	12/31/2023
VRTX	2,339,979	$952,135	12/31/2023
Invesco Ltd.	2,242,107	$912,291	12/31/2023
VRTX	2,242,107	$912,291	12/31/2023
Bank of New York Mellon Corp	1,874,129	$783,405	03/31/2024
VRTX	1,874,129	$783,405	03/31/2024
Deutsche Bank AG	1,646,665	$670,012	12/31/2023
VRTX	1,646,665	$670,012	12/31/2023
Renaissance Technologies LLC	1,591,688	$647,642	12/31/2023
VRTX	1,591,688	$647,642	12/31/2023
California Public Employees Retirement System	1,515,816	$616,770	12/31/2023
VRTX	1,515,816	$616,770	12/31/2023
Charles Schwab Investment Management Inc.	1,509,206	$614,081	12/31/2023
VRTX	1,509,206	$614,081	12/31/2023
Goldman Sachs Group Inc.		$603,473	12/31/2023
VRTX	1,484,934	$604,205	12/31/2023
Put	31,500	$12,817	12/31/2023
Call	29,700	$12,085	12/31/2023
Royal Bank of Canada	1,454,472	$591,810	12/31/2023
VRTX	1,454,472	$591,810	12/31/2023
Harding Loevner LP	1,321,229	$538,552	12/31/2023
VRTX	1,321,229	$538,552	12/31/2023
Pictet Asset Management Holding SA	1,081,046	$439,867	12/31/2023
VRTX	1,081,046	$439,867	12/31/2023
Winslow Capital Management LLC	925,369	$376,523	12/31/2023
VRTX	925,369	$376,523	12/31/2023
Nuveen Asset Management LLC	841,123	$342,245	12/31/2023
VRTX	841,123	$342,245	12/31/2023
The Manufacturers Life Insurance Company	818,803	$333,163	12/31/2023
VRTX	818,803	$333,163	12/31/2023
Swiss National Bank	807,100	$328,401	12/31/2023
VRTX	807,100	$328,401	12/31/2023
Caisse DE Depot ET Placement DU Quebec	803,726	$327,028	12/31/2023
VRTX	803,726	$327,028	12/31/2023
American Century Companies Inc.	800,537	$325,730	12/31/2023
VRTX	800,537	$325,730	12/31/2023
Voya Investment Management LLC	775,488	$315,002	12/31/2023
VRTX	775,488	$315,002	12/31/2023
Barclays PLC		$314,102	12/31/2023
VRTX	806,759	$328,262	12/31/2023
Put	36,000	$14,648	12/31/2023
Call	1,200	$488	12/31/2023
Wells Fargo & Company MN		$304,177	12/31/2023
VRTX	748,966	$304,747	12/31/2023
Put	1,400	$570	12/31/2023
Sumitomo Mitsui Trust Holdings Inc.	718,410	$300,303	03/31/2024
VRTX	718,410	$300,303	03/31/2024
Bellevue Group AG	736,390	$299,630	12/31/2023
VRTX	736,390	$299,630	12/31/2023
First Trust Advisors LP	734,835	$298,997	12/31/2023
VRTX	734,835	$298,997	12/31/2023
Mayflower Financial Advisors LLC	729,112	$296,668	12/31/2023
VRTX	729,112	$296,668	12/31/2023
Millennium Management LLC		$280,368	12/31/2023
VRTX	642,750	$261,529	12/31/2023
Call	152,100	$61,888	12/31/2023
Put	105,800	$43,049	12/31/2023
Franklin Resources Inc.	672,438	$273,608	12/31/2023
VRTX	672,438	$273,608	12/31/2023
Ensign Peak Advisors Inc	660,527	$268,762	12/31/2023
VRTX	660,527	$268,762	12/31/2023

See All: Funds Holding VRTX
See Details: Top 10 Hedge Funds Holding VRTX
Also See: VRTX Insider Buying
Also See: VRTX Holdings Changes
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