On this page, we present all of the funds holding SGEN from our database of 13F filers, detailed in the table below. The first column indicates the name of each of the funds holding SGEN, with a link to that fund's top holdings. The next columns indicate the amount of SGEN stock held by each of the funds holding SGEN, followed by the SGEN position size held by the fund, and lastly the date of the quarterly filing period the data represents. In total, we count 574 funds holding SGEN within the last two filing periods in our coverage universe of 13F filers, with the largest position size having been reported by Baker BROS. Advisors LP. For more details on the positions held by Baker BROS. Advisors LP (or by any of the other funds holding SGEN), click the fund name in the "Holder" column of the funds-holding-SGEN table below.

Holder	Amount	Position Size ($ in 1000's)	As of
Baker BROS. Advisors LP	46,913,769	$9,498,631	03/31/2023
SGEN	46,913,769	$9,498,631	03/31/2023
Capital International Investors	14,846,613	$3,006,143	03/31/2023
SGEN	14,846,613	$3,006,143	03/31/2023
Vanguard Group Inc.	13,167,969	$2,666,119	03/31/2023
SGEN	13,167,969	$2,666,119	03/31/2023
Capital World Investors	12,269,440	$2,484,194	03/31/2023
SGEN	12,269,440	$2,484,194	03/31/2023
BlackRock Inc.	11,191,122	$2,265,866	03/31/2023
SGEN	11,191,122	$2,265,866	03/31/2023
Wellington Management Group LLP	6,829,463	$1,382,761	03/31/2023
SGEN	6,829,463	$1,382,761	03/31/2023
Primecap Management Co. CA	4,894,808	$991,052	03/31/2023
SGEN	4,894,808	$991,052	03/31/2023
State Street Corp	3,354,232	$679,131	03/31/2023
SGEN	3,354,232	$679,131	03/31/2023
JPMorgan Chase & Co.		$557,501	03/31/2023
SGEN	3,330,600	$674,347	03/31/2023
Put	786,900	$159,324	03/31/2023
Call	209,800	$42,478	03/31/2023
Geode Capital Management LLC	1,974,023	$399,102	03/31/2023
SGEN	1,974,023	$399,102	03/31/2023
Avoro Capital Advisors LLC	1,801,906	$364,832	03/31/2023
SGEN	1,801,906	$364,832	03/31/2023
Quilter Plc	365	$362,445	03/31/2023
SGEN	365	$362,445	03/31/2023
T. Rowe Price Investment Management Inc.	1,622,223	$328,452	03/31/2023
SGEN	1,622,223	$328,452	03/31/2023
Price T Rowe Associates Inc. MD	1,580,816	$320,069	03/31/2023
SGEN	1,580,816	$320,069	03/31/2023
FMR LLC	1,437,343	$291,019	03/31/2023
SGEN	1,437,343	$291,019	03/31/2023
Franklin Resources Inc.	1,211,571	$245,307	03/31/2023
SGEN	1,211,571	$245,307	03/31/2023
Invesco Ltd.	1,094,118	$221,526	03/31/2023
SGEN	1,094,118	$221,526	03/31/2023
Pictet Asset Management SA	998,490	$202,164	03/31/2023
SGEN	998,490	$202,164	03/31/2023
Northern Trust Corp	903,311	$182,893	03/31/2023
SGEN	903,311	$182,893	03/31/2023
Macquarie Group Ltd.	896,308	$181,476	03/31/2023
SGEN	896,308	$181,476	03/31/2023
Bank of New York Mellon Corp	821,498	$166,329	03/31/2023
SGEN	821,498	$166,329	03/31/2023
Legal & General Group Plc	809,072	$163,813	03/31/2023
SGEN	809,072	$163,813	03/31/2023
Pentwater Capital Management LP		$162,341	03/31/2023
SGEN	1,755,000	$355,335	03/31/2023
Put	1,045,000	$211,581	03/31/2023
Call	91,800	$18,587	03/31/2023
UBS Asset Management Americas Inc.	761,009	$154,081	03/31/2023
SGEN	761,009	$154,081	03/31/2023
Millennium Management LLC		$142,467	03/31/2023
SGEN	739,541	$149,735	03/31/2023
Put	42,200	$8,544	03/31/2023
Call	6,300	$1,276	03/31/2023
Morgan Stanley	684,276	$138,546	03/31/2023
SGEN	684,276	$138,546	03/31/2023
Capital Group Private Client Services Inc.	682,659	$138,218	03/31/2023
SGEN	682,659	$138,218	03/31/2023
Voya Investment Management LLC	671,296	$135,917	03/31/2023
SGEN	671,296	$135,917	03/31/2023
ANTIPODES PARTNERS Ltd	591,342	$119,729	03/31/2023
SGEN	591,342	$119,729	03/31/2023
Assenagon Asset Management S.A.	571,796	$115,772	03/31/2023
SGEN	571,796	$115,772	03/31/2023
Swiss National Bank	552,700	$111,905	03/31/2023
SGEN	552,700	$111,905	03/31/2023
Polar Capital Holdings Plc	549,392	$111,235	03/31/2023
SGEN	549,392	$111,235	03/31/2023
Candriam Luxembourg S.C.A.	577,620	$107,645	03/31/2023
SGEN	577,620	$107,645	03/31/2023
Bank of America Corp DE		$106,817	03/31/2023
SGEN	527,569	$106,817	03/31/2023
Put	29,400	$5,953	03/31/2023
Call	29,400	$5,953	03/31/2023
Eagle Asset Management Inc.	525,787	$106,456	03/31/2023
SGEN	525,787	$106,456	03/31/2023
Deutsche Bank AG	509,276	$103,113	03/31/2023
SGEN	509,276	$103,113	03/31/2023
First Trust Advisors LP	495,791	$100,383	03/31/2023
SGEN	495,791	$100,383	03/31/2023
Charles Schwab Investment Management Inc.	486,396	$98,481	03/31/2023
SGEN	486,396	$98,481	03/31/2023
Sumitomo Mitsui Trust Holdings Inc.	447,334	$90,572	03/31/2023
SGEN	447,334	$90,572	03/31/2023
Point72 Asset Management L.P.	426,157	$86,284	03/31/2023
SGEN	426,157	$86,284	03/31/2023
Rock Springs Capital Management LP	400,200	$81,028	03/31/2023
SGEN	400,200	$81,028	03/31/2023
Adage Capital Partners GP L.L.C.	400,000	$80,988	03/31/2023
SGEN	400,000	$80,988	03/31/2023
Nuveen Asset Management LLC	379,803	$76,899	03/31/2023
SGEN	379,803	$76,899	03/31/2023
Alpine Associates Management Inc.	372,600	$75,440	03/31/2023
SGEN	372,600	$75,440	03/31/2023
Balyasny Asset Management LLC		$75,315	03/31/2023
SGEN	317,380	$64,260	03/31/2023
Call	54,600	$11,055	03/31/2023
Principal Financial Group Inc.	319,598	$64,709	03/31/2023
SGEN	319,598	$64,709	03/31/2023
APG Asset Management N.V.	341,423	$63,627	03/31/2023
SGEN	341,423	$63,627	03/31/2023
Caisse DE Depot ET Placement DU Quebec	312,196	$63,210	03/31/2023
SGEN	312,196	$63,210	03/31/2023
Citadel Advisors LLC		$62,188	03/31/2023
SGEN	383,946	$77,738	03/31/2023
Put	117,000	$23,689	03/31/2023
Call	40,200	$8,139	03/31/2023
Dimensional Fund Advisors LP	304,363	$61,625	03/31/2023
SGEN	304,363	$61,625	03/31/2023
Goldman Sachs Group Inc.		$60,300	03/31/2023
SGEN	294,123	$59,551	03/31/2023
Call	3,700	$749	03/31/2023
California Public Employees Retirement System	296,338	$60,000	03/31/2023
SGEN	296,338	$60,000	03/31/2023
Hsbc Holdings PLC		$58,767	03/31/2023
SGEN	311,589	$63,257	03/31/2023
Put	29,900	$6,074	03/31/2023
Call	7,800	$1,584	03/31/2023
Magnetar Financial LLC	282,533	$57,204	03/31/2023
SGEN	282,533	$57,204	03/31/2023
Paradigm Biocapital Advisors LP	281,969	$57,090	03/31/2023
SGEN	281,969	$57,090	03/31/2023
Eventide Asset Management LLC	279,834	$56,658	03/31/2023
SGEN	279,834	$56,658	03/31/2023
Capital International Inc.	278,279	$56,343	03/31/2023
SGEN	278,279	$56,343	03/31/2023
Amundi	274,460	$56,264	03/31/2023
SGEN	274,460	$56,264	03/31/2023
Zevenbergen Capital Investments LLC	272,576	$55,188	03/31/2023
SGEN	272,576	$55,188	03/31/2023
Credit Suisse AG	256,273	$51,888	03/31/2023
SGEN	256,273	$51,888	03/31/2023
Marshall Wace LLP	233,803	$47,338	03/31/2023
SGEN	233,803	$47,338	03/31/2023
California State Teachers Retirement System	231,875	$46,948	03/31/2023
SGEN	231,875	$46,948	03/31/2023
TD Asset Management Inc.	227,962	$46,155	03/31/2023
SGEN	227,962	$46,155	03/31/2023
Tekla Capital Management LLC	224,663	$45,488	03/31/2023
SGEN	224,663	$45,488	03/31/2023
Barclays PLC		$44,733	03/31/2023
SGEN	222,440	$45,037	03/31/2023
Put	1,500	$304	03/31/2023
PFM Health Sciences LP	220,883	$44,722	03/31/2023
SGEN	220,883	$44,722	03/31/2023
Royal Bank of Canada	219,022	$44,344	03/31/2023
SGEN	219,022	$44,344	03/31/2023
Melqart Asset Management UK Ltd	214,708	$43,472	03/31/2023
SGEN	214,708	$43,472	03/31/2023
National Pension Service	206,092	$41,853	03/31/2023
SGEN	206,092	$41,853	03/31/2023
Citigroup Inc.		$40,841	03/31/2023
SGEN	165,013	$33,410	03/31/2023
Call	36,700	$7,431	03/31/2023
International Biotechnology Trust PLC	200,200	$40,510	03/31/2023
SGEN	200,200	$40,510	03/31/2023
Boxer Capital LLC	200,000	$40,494	03/31/2023
SGEN	200,000	$40,494	03/31/2023
Pinnacle Associates Ltd.	194,038	$39,287	03/31/2023
SGEN	194,038	$39,287	03/31/2023
Sand Grove Capital Management LLP	190,396	$38,549	03/31/2023
SGEN	190,396	$38,549	03/31/2023
Jane Street Group LLC		$35,597	03/31/2023
Call	196,000	$39,684	03/31/2023
Put	91,500	$18,526	03/31/2023
SGEN	71,312	$14,439	03/31/2023
Eagle Health Investments LP	174,902	$35,412	03/31/2023
SGEN	174,902	$35,412	03/31/2023
Jennison Associates LLC	171,823	$34,789	03/31/2023
SGEN	171,823	$34,789	03/31/2023
ProShare Advisors LLC	170,288	$34,478	03/31/2023
SGEN	170,288	$34,478	03/31/2023
Rhumbline Advisers	167,965	$34,008	03/31/2023
SGEN	167,965	$34,008	03/31/2023
Capital Group Investment Management PTE. LTD.	165,326	$33,474	03/31/2023
SGEN	165,326	$33,474	03/31/2023
Employees Retirement System of Texas	162,000	$32,800	03/31/2023
SGEN	162,000	$32,800	03/31/2023
Susquehanna International Group LLP		$32,553	03/31/2023
Call	437,300	$88,540	03/31/2023
Put	347,400	$70,338	03/31/2023
SGEN	70,878	$14,351	03/31/2023
Group One Trading L.P.		$32,314	03/31/2023
Call	220,700	$44,685	03/31/2023
Put	61,100	$12,371	03/31/2023
Canada Pension Plan Investment Board	159,580	$32,310	03/31/2023
SGEN	159,580	$32,310	03/31/2023
Mirae Asset Global Investments Co. Ltd.	154,316	$31,244	03/31/2023
SGEN	154,316	$31,244	03/31/2023
State Board of Administration of Florida Retirement System	152,429	$30,862	03/31/2023
SGEN	152,429	$30,862	03/31/2023
Davide Leone & Partners Investment Co Ltd.	151,000	$30,573	03/31/2023
SGEN	151,000	$30,573	03/31/2023
Allianz Asset Management GmbH	149,944	$30,359	03/31/2023
SGEN	149,944	$30,359	03/31/2023
New York State Common Retirement Fund	142,423	$28,836	03/31/2023
SGEN	142,423	$28,836	03/31/2023
HRT Financial LP	140,093	$28,364	03/31/2023
SGEN	140,093	$28,364	03/31/2023
Capital International Sarl	136,974	$27,733	03/31/2023
SGEN	136,974	$27,733	03/31/2023
DekaBank Deutsche Girozentrale	136,085	$27,407	03/31/2023
SGEN	136,085	$27,407	03/31/2023
Novo Holdings A S	134,986	$27,331	03/31/2023
SGEN	134,986	$27,331	03/31/2023
Allspring Global Investments Holdings LLC	133,545	$27,039	03/31/2023
SGEN	133,545	$27,039	03/31/2023
Victory Capital Management Inc.	132,567	$26,841	03/31/2023
SGEN	132,567	$26,841	03/31/2023
Cerity Partners LLC	2,155	$26,098	03/31/2023
SGEN	2,155	$26,098	03/31/2023
Westchester Capital Management LLC	123,287	$24,962	03/31/2023
SGEN	123,287	$24,962	03/31/2023
Voloridge Investment Management LLC	121,973	$24,696	03/31/2023
SGEN	121,973	$24,696	03/31/2023
Capital International Ltd.	121,529	$24,606	03/31/2023
SGEN	121,529	$24,606	03/31/2023
UBS Group AG	118,878	$24,069	03/31/2023
SGEN	118,878	$24,069	03/31/2023
Korea Investment CORP	116,786	$23,646	03/31/2023
SGEN	116,786	$23,646	03/31/2023
Mitsubishi UFJ Trust & Banking Corp	116,126	$23,512	03/31/2023
SGEN	116,126	$23,512	03/31/2023
Wells Fargo & Company MN	115,552	$23,396	03/31/2023
SGEN	115,552	$23,396	03/31/2023
Van ECK Associates Corp	112,546	$22,787	03/31/2023
SGEN	112,546	$22,787	03/31/2023
AXA S.A.	111,991	$22,675	03/31/2023
SGEN	111,991	$22,675	03/31/2023
State of Wisconsin Investment Board	110,392	$22,351	03/31/2023
SGEN	110,392	$22,351	03/31/2023
Asset Management One Co. Ltd.	109,953	$22,262	03/31/2023
SGEN	109,953	$22,262	03/31/2023
Water Island Capital LLC	108,429	$21,954	03/31/2023
SGEN	108,429	$21,954	03/31/2023
Neuberger Berman Group LLC	103,870	$21,031	03/31/2023
SGEN	103,870	$21,031	03/31/2023
Kynam Capital Management LP	100,000	$20,247	03/31/2023
SGEN	100,000	$20,247	03/31/2023
Alliancebernstein L.P.	97,402	$19,721	03/31/2023
SGEN	97,402	$19,721	03/31/2023
CNH Partners LLC	97,082	$19,656	03/31/2023
SGEN	97,082	$19,656	03/31/2023
FIL Ltd	87,728	$17,762	03/31/2023
SGEN	87,728	$17,762	03/31/2023
Hudson Bay Capital Management LP	86,414	$17,496	03/31/2023
SGEN	86,414	$17,496	03/31/2023
Blair William & Co. IL	85,570	$17,325	03/31/2023
SGEN	85,570	$17,325	03/31/2023
State of New Jersey Common Pension Fund D	83,767	$16,960	03/31/2023
SGEN	83,767	$16,960	03/31/2023
Ameriprise Financial Inc.	78,739	$15,942	03/31/2023
SGEN	78,739	$15,942	03/31/2023
Los Angeles Capital Management & Equity Research Inc.	76,484	$15,486	03/31/2023
SGEN	76,484	$15,486	03/31/2023
Calamos Advisors LLC	75,808	$15,349	03/31/2023
SGEN	75,808	$15,349	03/31/2023
Parkman Healthcare Partners LLC	73,100	$14,801	03/31/2023
SGEN	73,100	$14,801	03/31/2023
Soleus Capital Management L.P.	71,000	$14,375	03/31/2023
SGEN	71,000	$14,375	03/31/2023
Public Employees Retirement System of Ohio	70,833	$14,342	03/31/2023
SGEN	70,833	$14,342	03/31/2023
Woodline Partners LP	70,350	$14,244	03/31/2023
SGEN	70,350	$14,244	03/31/2023
Qube Research & Technologies Ltd	69,666	$14,105	03/31/2023
SGEN	69,666	$14,105	03/31/2023
KBC Group NV	69,186	$14,008	03/31/2023
SGEN	69,186	$14,008	03/31/2023
DNB Asset Management AS	66,440	$13,452	03/31/2023
SGEN	66,440	$13,452	03/31/2023
Great West Life Assurance Co. Can	65,452	$13,272	03/31/2023
SGEN	65,452	$13,272	03/31/2023
Rafferty Asset Management LLC	65,389	$13,239	03/31/2023
SGEN	65,389	$13,239	03/31/2023
BNP PARIBAS ASSET MANAGEMENT Holding S.A.	63,919	$12,942	03/31/2023
SGEN	63,919	$12,942	03/31/2023
Artisan Partners Limited Partnership	62,500	$12,654	03/31/2023
SGEN	62,500	$12,654	03/31/2023
Walleye Trading LLC		$12,594	03/31/2023
Call	167,600	$33,934	03/31/2023
Put	105,400	$21,340	03/31/2023
Guggenheim Capital LLC	61,987	$12,551	03/31/2023
SGEN	61,987	$12,551	03/31/2023
The Manufacturers Life Insurance Company	60,728	$12,296	03/31/2023
SGEN	60,728	$12,296	03/31/2023
Mitsubishi UFJ Kokusai Asset Management Co. Ltd.	60,511	$12,252	03/31/2023
SGEN	60,511	$12,252	03/31/2023
Brookfield Asset Management Inc.		$12,067	03/31/2023
Call	54,600	$11,055	03/31/2023
SGEN	5,000	$1,012	03/31/2023
Treasurer of the State of North Carolina	59,443	$12,035	03/31/2023
SGEN	59,443	$12,035	03/31/2023
Advisor Group Holdings Inc.	54,380	$11,023	03/31/2023
SGEN	54,380	$11,023	03/31/2023
Sei Investments Co.	53,990	$10,929	03/31/2023
SGEN	53,990	$10,929	03/31/2023
Handelsbanken Fonder AB	53,115	$10,754	03/31/2023
SGEN	53,115	$10,754	03/31/2023
Cullen Frost Bankers Inc.	52,496	$10,629	03/31/2023
SGEN	52,496	$10,629	03/31/2023
Envestnet Asset Management Inc.	52,024	$10,533	03/31/2023
SGEN	52,024	$10,533	03/31/2023
Artia Global Partners LP	51,175	$10,361	03/31/2023
SGEN	51,175	$10,361	03/31/2023
Daymark Wealth Partners LLC	49,547	$10,032	03/31/2023
SGEN	49,547	$10,032	03/31/2023
Westpac Banking Corp	48,744	$9,869	03/31/2023
SGEN	48,744	$9,869	03/31/2023
Andra AP fonden	48,400	$9,800	03/31/2023
SGEN	48,400	$9,800	03/31/2023
Royal London Asset Management Ltd.	47,701	$9,658	03/31/2023
SGEN	47,701	$9,658	03/31/2023
Man Group plc	47,650	$9,648	03/31/2023
SGEN	47,650	$9,648	03/31/2023
Nan Fung Group Holdings Ltd	47,096	$9,536	03/31/2023
SGEN	47,096	$9,536	03/31/2023
Fjarde AP Fonden Fourth Swedish National Pension Fund	46,959	$9,508	03/31/2023
SGEN	46,959	$9,508	03/31/2023
EFG Asset Management North America Corp.	45,855	$9,282	03/31/2023
SGEN	45,855	$9,282	03/31/2023
Toronto Dominion Bank	45,853	$9,279	03/31/2023
SGEN	45,853	$9,279	03/31/2023
Skandinaviska Enskilda Banken AB publ	45,572	$9,227	03/31/2023
SGEN	45,572	$9,227	03/31/2023
Nomura Asset Management Co. Ltd.	44,305	$8,970	03/31/2023
SGEN	44,305	$8,970	03/31/2023
Weiss Multi Strategy Advisers LLC	43,832	$8,875	03/31/2023
SGEN	43,832	$8,875	03/31/2023
Banque Pictet & Cie SA	41,662	$8,435	03/31/2023
SGEN	41,662	$8,435	03/31/2023
Rhenman & Partners Asset Management AB	41,000	$8,326	03/31/2023
SGEN	41,000	$8,326	03/31/2023
Squarepoint Ops LLC	39,023	$7,901	03/31/2023
SGEN	39,023	$7,901	03/31/2023
USS Investment Management Ltd	38,601	$7,813	03/31/2023
SGEN	38,601	$7,813	03/31/2023
Bank of Montreal Can	58,999	$7,796	12/31/2022
SGEN	58,999	$7,796	12/31/2022
Hillhouse Capital Advisors LTD.	38,350	$7,765	03/31/2023
SGEN	38,350	$7,765	03/31/2023
Arizona State Retirement System	38,020	$7,698	03/31/2023
SGEN	38,020	$7,698	03/31/2023
D. E. Shaw & Co. Inc.		$7,640	03/31/2023
Call	20,000	$4,049	03/31/2023
SGEN	17,735	$3,591	03/31/2023
Crabel Capital Management LLC	37,637	$7,620	03/31/2023
SGEN	37,637	$7,620	03/31/2023
Lagoda Investment Management L.P.	36,545	$7,399	03/31/2023
SGEN	36,545	$7,399	03/31/2023
Sector Gamma AS	36,000	$7,289	03/31/2023
SGEN	36,000	$7,289	03/31/2023
IFG Advisory LLC	34,270	$6,939	03/31/2023
SGEN	34,270	$6,939	03/31/2023
Teacher Retirement System of Texas	32,582	$6,597	03/31/2023
SGEN	32,582	$6,597	03/31/2023
Partners Capital Investment Group LLP	31,965	$6,472	03/31/2023
SGEN	31,965	$6,472	03/31/2023
Athos Capital Ltd	31,000	$6,277	03/31/2023
SGEN	31,000	$6,277	03/31/2023
Prudential Financial Inc.	31,379	$6,227	03/31/2023
SGEN	31,379	$6,227	03/31/2023
Raymond James & Associates	29,655	$6,004	03/31/2023
SGEN	29,655	$6,004	03/31/2023
Natixis Advisors L.P.	29,601	$5,993	03/31/2023
SGEN	29,601	$5,993	03/31/2023
Citizens Business Bank	29,015	$5,875	03/31/2023
SGEN	29,015	$5,875	03/31/2023
Mackenzie Financial Corp	28,317	$5,733	03/31/2023
SGEN	28,317	$5,733	03/31/2023
Forsta AP Fonden	28,200	$5,710	03/31/2023
SGEN	28,200	$5,710	03/31/2023
CIBC Asset Management Inc	27,450	$5,558	03/31/2023
SGEN	27,450	$5,558	03/31/2023
IFM Investors Pty Ltd	27,036	$5,474	03/31/2023
SGEN	27,036	$5,474	03/31/2023
ARP Americas LP	26,801	$5,426	03/31/2023
SGEN	26,801	$5,426	03/31/2023
Gabelli Funds LLC	26,300	$5,325	03/31/2023
SGEN	26,300	$5,325	03/31/2023
National Bank of Canada FI	26,140	$5,283	03/31/2023
SGEN	26,140	$5,283	03/31/2023
Zurcher Kantonalbank Zurich Cantonalbank	25,684	$5,200	03/31/2023
SGEN	25,684	$5,200	03/31/2023
Carlson Capital L P	25,000	$5,062	03/31/2023
SGEN	25,000	$5,062	03/31/2023
Berry Street Capital Management LLP	25,000	$5,062	03/31/2023
SGEN	25,000	$5,062	03/31/2023
Wealthfront Advisers LLC	24,934	$5,048	03/31/2023
SGEN	24,934	$5,048	03/31/2023
Baird Financial Group Inc.	24,900	$5,042	03/31/2023
SGEN	24,900	$5,042	03/31/2023
Tokio Marine Asset Management Co. Ltd.	24,878	$5,037	03/31/2023
SGEN	24,878	$5,037	03/31/2023
Standard Life Aberdeen plc	24,652	$4,991	03/31/2023
SGEN	24,652	$4,991	03/31/2023
Utah Retirement Systems	24,240	$4,908	03/31/2023
SGEN	24,240	$4,908	03/31/2023
Stifel Financial Corp	24,085	$4,876	03/31/2023
SGEN	24,085	$4,876	03/31/2023
CWM LLC	23,484	$4,755	03/31/2023
SGEN	23,484	$4,755	03/31/2023
Bellevue Group AG	22,700	$4,596	03/31/2023
SGEN	22,700	$4,596	03/31/2023
Public Employees Retirement Association of Colorado	22,429	$4,541	03/31/2023
SGEN	22,429	$4,541	03/31/2023
Simplex Trading LLC		$4,517	03/31/2023
Call	41,000	$8,301	03/31/2023
Put	19,300	$3,907	03/31/2023
SGEN	608	$123	03/31/2023
HighVista Strategies LLC	21,948	$4,444	03/31/2023
SGEN	21,948	$4,444	03/31/2023
Prelude Capital Management LLC	21,518	$4,357	03/31/2023
SGEN	21,518	$4,357	03/31/2023
Gotham Asset Management LLC	21,106	$4,273	03/31/2023
SGEN	21,106	$4,273	03/31/2023
AGF Management Ltd.	20,946	$4,241	03/31/2023
SGEN	20,946	$4,241	03/31/2023
Russell Investments Group Ltd.	20,203	$4,090	03/31/2023
SGEN	20,203	$4,090	03/31/2023
EFG Asset Management Americas Corp.	20,006	$4,051	03/31/2023
SGEN	20,006	$4,051	03/31/2023
Affinity Asset Advisors LLC	20,000	$4,049	03/31/2023
SGEN	20,000	$4,049	03/31/2023
Robeco Institutional Asset Management B.V.	19,444	$3,937	03/31/2023
SGEN	19,444	$3,937	03/31/2023
Sectoral Asset Management Inc	19,350	$3,918	03/31/2023
SGEN	19,350	$3,918	03/31/2023
Gateway Investment Advisers LLC	18,966	$3,840	03/31/2023
SGEN	18,966	$3,840	03/31/2023
Schonfeld Strategic Advisors LLC		$3,816	03/31/2023
SGEN	18,890	$3,825	03/31/2023
Put	50,000	$9	03/31/2023
Xponance Inc.	18,581	$3,762	03/31/2023
SGEN	18,581	$3,762	03/31/2023
Gulf International Bank UK Ltd	18,201	$3,685	03/31/2023
SGEN	18,201	$3,685	03/31/2023
Ergoteles LLC	17,733	$3,590	03/31/2023
SGEN	17,733	$3,590	03/31/2023
Fairfield Bush & CO.	17,641	$3,572	03/31/2023
SGEN	17,641	$3,572	03/31/2023
Advisors Asset Management Inc.	17,065	$3,455	03/31/2023
SGEN	17,065	$3,455	03/31/2023
Janus Henderson Group PLC	17,052	$3,452	03/31/2023
SGEN	17,052	$3,452	03/31/2023
Intech Investment Management LLC	16,924	$3,427	03/31/2023
SGEN	16,924	$3,427	03/31/2023
Truist Financial Corp	16,792	$3,400	03/31/2023
SGEN	16,792	$3,400	03/31/2023
Beacon Investment Advisory Services Inc.	16,698	$3,381	03/31/2023
SGEN	16,698	$3,381	03/31/2023
Janney Montgomery Scott LLC	16,375	$3,315	03/31/2023
SGEN	16,375	$3,315	03/31/2023
Nissay Asset Management Corp Japan ADV	16,302	$3,301	03/31/2023
SGEN	16,302	$3,301	03/31/2023
Brown Advisory Inc.	16,294	$3,299	03/31/2023
SGEN	16,294	$3,299	03/31/2023
Frontier Capital Management Co. LLC	16,098	$3,259	03/31/2023
SGEN	16,098	$3,259	03/31/2023
Illinois Municipal Retirement Fund	16,010	$3,242	03/31/2023
SGEN	16,010	$3,242	03/31/2023
Sivik Global Healthcare LLC	16,000	$3,240	03/31/2023
SGEN	16,000	$3,240	03/31/2023
GABELLI & Co INVESTMENT ADVISERS INC.	15,900	$3,219	03/31/2023
SGEN	15,900	$3,219	03/31/2023
Amalgamated Bank	15,603	$3,159	03/31/2023
SGEN	15,603	$3,159	03/31/2023
Daiwa Securities Group Inc.	15,586	$3,156	03/31/2023
SGEN	15,586	$3,156	03/31/2023
Grandfield & Dodd LLC	15,403	$3,119	03/31/2023
SGEN	15,403	$3,119	03/31/2023
LPL Financial LLC	15,203	$3,078	03/31/2023
SGEN	15,203	$3,078	03/31/2023
FORA Capital LLC	15,145	$3,066	03/31/2023
SGEN	15,145	$3,066	03/31/2023
Equitec Proprietary Markets LLC		$3,037	03/31/2023
Call	20,700	$4,191	03/31/2023
Put	6,200	$1,255	03/31/2023
SGEN	500	$101	03/31/2023
Profund Advisors LLC	14,914	$3,020	03/31/2023
SGEN	14,914	$3,020	03/31/2023
Shelton Capital Management	14,644	$2,965	03/31/2023
SGEN	14,644	$2,965	03/31/2023
New York Life Investment Management LLC	14,455	$2,927	03/31/2023
SGEN	14,455	$2,927	03/31/2023
SG Americas Securities LLC	14,277	$2,891	03/31/2023
SGEN	14,277	$2,891	03/31/2023
Cubist Systematic Strategies LLC	14,214	$2,878	03/31/2023
SGEN	14,214	$2,878	03/31/2023
Connor Clark & Lunn Investment Management Ltd.	14,032	$2,841	03/31/2023
SGEN	14,032	$2,841	03/31/2023
Knights of Columbus Asset Advisors LLC	13,738	$2,782	03/31/2023
SGEN	13,738	$2,782	03/31/2023
Gamco Investors INC. ET AL	13,350	$2,703	03/31/2023
SGEN	13,350	$2,703	03/31/2023
Walleye Capital LLC		$2,609	03/31/2023
Call	10,400	$2,106	03/31/2023
SGEN	2,787	$564	03/31/2023
Put	300	$61	03/31/2023
Parkwood LLC	12,618	$2,555	03/31/2023
SGEN	12,618	$2,555	03/31/2023
Clear Street Markets LLC		$2,531	03/31/2023
Call	32,500	$6,580	03/31/2023
Put	20,000	$4,049	03/31/2023
BRITISH COLUMBIA INVESTMENT MANAGEMENT Corp	12,398	$2,510	03/31/2023
SGEN	12,398	$2,510	03/31/2023
DCF Advisers LLC	12,150	$2,460	03/31/2023
SGEN	12,150	$2,460	03/31/2023
American International Group Inc.	12,080	$2,446	03/31/2023
SGEN	12,080	$2,446	03/31/2023
ING Groep NV	11,901	$2,410	03/31/2023
SGEN	11,901	$2,410	03/31/2023
Mirabella Financial Services LLP	9,757	$2,396	03/31/2023
SGEN	9,757	$2,396	03/31/2023
Snider Financial Group	11,717	$2,372	03/31/2023
SGEN	11,717	$2,372	03/31/2023
Two Sigma Investments LP	11,705	$2,370	03/31/2023
SGEN	11,705	$2,370	03/31/2023
Sumitomo Mitsui DS Asset Management Company Ltd	11,707	$2,370	03/31/2023
SGEN	11,707	$2,370	03/31/2023
Creative Planning	11,349	$2,298	03/31/2023
SGEN	11,349	$2,298	03/31/2023
Industrial Alliance Investment Management Inc.	11,234	$2,275	03/31/2023
SGEN	11,234	$2,275	03/31/2023
Elo Mutual Pension Insurance Co	11,170	$2,262	03/31/2023
SGEN	11,170	$2,262	03/31/2023
Point72 Middle East FZE	11,071	$2,242	03/31/2023
SGEN	11,071	$2,242	03/31/2023
Wolverine Asset Management LLC	10,775	$2,182	03/31/2023
SGEN	10,775	$2,182	03/31/2023
Maryland State Retirement & Pension System	10,752	$2,177	03/31/2023
SGEN	10,752	$2,177	03/31/2023
Renaissance Technologies LLC	10,700	$2,166	03/31/2023
SGEN	10,700	$2,166	03/31/2023
Pacer Advisors Inc.	10,589	$2,144	03/31/2023
SGEN	10,589	$2,144	03/31/2023
Bayesian Capital Management LP	10,500	$2,126	03/31/2023
SGEN	10,500	$2,126	03/31/2023
Mariner LLC	10,350	$2,096	03/31/2023
SGEN	10,350	$2,096	03/31/2023
Linden Thomas Advisory Services LLC	10,250	$2,075	03/31/2023
SGEN	10,250	$2,075	03/31/2023
EHP Funds Inc.	10,000	$2,025	03/31/2023
SGEN	10,000	$2,025	03/31/2023
Strs Ohio	10,000	$2,024	03/31/2023
SGEN	10,000	$2,024	03/31/2023
Addison Capital Co	9,749	$1,974	03/31/2023
SGEN	9,749	$1,974	03/31/2023
Copperwynd Financial LLC	9,672	$1,958	03/31/2023
SGEN	9,672	$1,958	03/31/2023
MML Investors Services LLC	9,553	$1,934	03/31/2023
SGEN	9,553	$1,934	03/31/2023
American Century Companies Inc.	9,453	$1,900	03/31/2023
SGEN	9,453	$1,900	03/31/2023
Louisiana State Employees Retirement System	9,300	$1,883	03/31/2023
SGEN	9,300	$1,883	03/31/2023
AIA Group Ltd	9,126	$1,848	03/31/2023
SGEN	9,126	$1,848	03/31/2023
Seeyond	14,342	$1,843	12/31/2022
SGEN	14,342	$1,843	12/31/2022
Martingale Asset Management L P	8,996	$1,821	03/31/2023
SGEN	8,996	$1,821	03/31/2023
Panagora Asset Management Inc.	8,968	$1,816	03/31/2023
SGEN	8,968	$1,816	03/31/2023
Assetmark Inc.	8,957	$1,814	03/31/2023
SGEN	8,957	$1,814	03/31/2023
WINTON GROUP Ltd	8,914	$1,805	03/31/2023
SGEN	8,914	$1,805	03/31/2023
Siemens Fonds Invest GmbH	8,833	$1,788	03/31/2023
SGEN	8,833	$1,788	03/31/2023
Schroder Investment Management Group	8,778	$1,777	03/31/2023
SGEN	8,778	$1,777	03/31/2023
Nordea Investment Management AB	8,741	$1,777	03/31/2023
SGEN	8,741	$1,777	03/31/2023
AQR Capital Management LLC	8,682	$1,758	03/31/2023
SGEN	8,682	$1,758	03/31/2023
Dai Ichi Life Insurance Company Ltd	8,331	$1,687	03/31/2023
SGEN	8,331	$1,687	03/31/2023
MetLife Investment Management LLC	8,239	$1,668	03/31/2023
SGEN	8,239	$1,668	03/31/2023
CI Private Wealth LLC	8,069	$1,634	03/31/2023
SGEN	8,069	$1,634	03/31/2023
Raymond James Financial Services Advisors Inc.	8,042	$1,628	03/31/2023
SGEN	8,042	$1,628	03/31/2023
Commonwealth Equity Services LLC	7,997	$1,619	03/31/2023
SGEN	7,997	$1,619	03/31/2023
Oppenheimer & Co. Inc.	7,886	$1,597	03/31/2023
SGEN	7,886	$1,597	03/31/2023
United Capital Financial Advisers LLC	7,844	$1,588	03/31/2023
SGEN	7,844	$1,588	03/31/2023
US Bancorp DE	7,823	$1,584	03/31/2023
SGEN	7,823	$1,584	03/31/2023
Pioneer Trust Bank N A OR	7,800	$1,579	03/31/2023
SGEN	7,800	$1,579	03/31/2023
PEAK6 Investments LLC		$1,579	03/31/2023
Call	7,800	$1,579	03/31/2023
Sawtooth Solutions LLC	7,607	$1,540	03/31/2023
SGEN	7,607	$1,540	03/31/2023
Bleakley Financial Group LLC	7,592	$1,537	03/31/2023
SGEN	7,592	$1,537	03/31/2023
Nwam LLC	7,583	$1,535	03/31/2023
SGEN	7,583	$1,535	03/31/2023
Y.D. More Investments Ltd	7,500	$1,519	03/31/2023
SGEN	7,500	$1,519	03/31/2023
Elite Wealth Management Inc.	7,471	$1,513	03/31/2023
SGEN	7,471	$1,513	03/31/2023
The PNC Financial Services Group Inc.	7,470	$1,512	03/31/2023
SGEN	7,470	$1,512	03/31/2023
Orser Capital Management LLC	7,240	$1,466	03/31/2023
SGEN	7,240	$1,466	03/31/2023
Keybank National Association OH	7,076	$1,433	03/31/2023
SGEN	7,076	$1,433	03/31/2023
BCK Capital Management LP	7,000	$1,417	03/31/2023
SGEN	7,000	$1,417	03/31/2023
JustInvest LLC	6,790	$1,375	03/31/2023
SGEN	6,790	$1,375	03/31/2023
Harvest Volatility Management LLC	6,608	$1,342	03/31/2023
SGEN	6,608	$1,342	03/31/2023
Alpine Global Management LLC	6,450	$1,306	03/31/2023
SGEN	6,450	$1,306	03/31/2023
Northwestern Mutual Wealth Management Co.	6,433	$1,302	03/31/2023
SGEN	6,433	$1,302	03/31/2023
Verition Fund Management LLC	6,416	$1,299	03/31/2023
SGEN	6,416	$1,299	03/31/2023
Liontrust Investment Partners LLP	6,099	$1,235	03/31/2023
SGEN	6,099	$1,235	03/31/2023
Ostrum Asset Management	6,063	$1,228	03/31/2023
SGEN	6,063	$1,228	03/31/2023
Verity Asset Management Inc.	5,929	$1,200	03/31/2023
SGEN	5,929	$1,200	03/31/2023
Vontobel Holding Ltd.	5,892	$1,193	03/31/2023
SGEN	5,892	$1,193	03/31/2023
B. Metzler seel. Sohn & Co. AG	5,769	$1,168	03/31/2023
SGEN	5,769	$1,168	03/31/2023
Nomura Holdings Inc.	5,750	$1,164	03/31/2023
SGEN	5,750	$1,164	03/31/2023
Captrust Financial Advisors	5,494	$1,112	03/31/2023
SGEN	5,494	$1,112	03/31/2023
Prudential PLC	5,405	$1,094	03/31/2023
SGEN	5,405	$1,094	03/31/2023
Meiji Yasuda Asset Management Co Ltd.	5,288	$1,071	03/31/2023
SGEN	5,288	$1,071	03/31/2023
Plancorp LLC	5,265	$1,066	03/31/2023
SGEN	5,265	$1,066	03/31/2023
M&T Bank Corp	5,241	$1,061	03/31/2023
SGEN	5,241	$1,061	03/31/2023
Bank of Nova Scotia	5,178	$1,048	03/31/2023
SGEN	5,178	$1,048	03/31/2023
Aviva PLC	5,178	$1,048	03/31/2023
SGEN	5,178	$1,048	03/31/2023
Veriti Management LLC	5,028	$1,018	03/31/2023
SGEN	5,028	$1,018	03/31/2023
Aquila Investment Management LLC	5,000	$1,012	03/31/2023
SGEN	5,000	$1,012	03/31/2023
Knott David M Jr	5,000	$1,012	03/31/2023
SGEN	5,000	$1,012	03/31/2023
Wolverine Trading LLC		$954	03/31/2023
Call	11,400	$2,315	03/31/2023
Put	6,700	$1,361	03/31/2023
Associated Banc Corp	4,667	$945	03/31/2023
SGEN	4,667	$945	03/31/2023
Duality Advisers LP	7,335	$943	12/31/2022
SGEN	7,335	$943	12/31/2022
ExodusPoint Capital Management LP	4,600	$931	03/31/2023
SGEN	4,600	$931	03/31/2023
Cetera Investment Advisers	4,526	$916	03/31/2023
SGEN	4,526	$916	03/31/2023
Yarbrough Capital LLC	4,526	$916	03/31/2023
SGEN	4,526	$916	03/31/2023
Moser Wealth Advisors LLC	7,090	$911	12/31/2022
SGEN	7,090	$911	12/31/2022
FNY Investment Advisers LLC	4,420	$894	03/31/2023
SGEN	4,420	$894	03/31/2023
Commerce Bank	4,405	$892	03/31/2023
SGEN	4,405	$892	03/31/2023
Lattice Capital Management LLC	4,400	$891	03/31/2023
SGEN	4,400	$891	03/31/2023
Parcion Private Wealth LLC	4,320	$875	03/31/2023
SGEN	4,320	$875	03/31/2023
Meiji Yasuda Life Insurance Co	4,207	$852	03/31/2023
SGEN	4,207	$852	03/31/2023
Natixis	4,160	$842	03/31/2023
SGEN	4,160	$842	03/31/2023
Ethic Inc.	4,154	$841	03/31/2023
SGEN	4,154	$841	03/31/2023
Tower Research Capital LLC TRC	4,039	$818	03/31/2023
SGEN	4,039	$818	03/31/2023
Cypress Financial Planning LLC	4,050	$818	03/31/2023
SGEN	4,050	$818	03/31/2023
Ameritas Investment Partners Inc.	4,001	$810	03/31/2023
SGEN	4,001	$810	03/31/2023
Whittier Trust Co.	3,948	$799	03/31/2023
SGEN	3,948	$799	03/31/2023
Allstate Investment Management Co.	6,207	$798	12/31/2022
SGEN	6,207	$798	12/31/2022
Western Financial Corp CA	3,911	$792	03/31/2023
SGEN	3,911	$792	03/31/2023
E Fund Management Co. Ltd.	3,902	$790	03/31/2023
SGEN	3,902	$790	03/31/2023
HighTower Advisors LLC	3,900	$785	03/31/2023
SGEN	3,900	$785	03/31/2023
Retireful LLC	3,841	$778	03/31/2023
SGEN	3,841	$778	03/31/2023
Vident Investment Advisory LLC	3,767	$763	03/31/2023
SGEN	3,767	$763	03/31/2023
Reynders McVeigh Capital Management LLC	3,715	$752	03/31/2023
SGEN	3,715	$752	03/31/2023
Cetera Advisor Networks LLC	3,709	$751	03/31/2023
SGEN	3,709	$751	03/31/2023
Values First Advisors Inc.	3,636	$736	03/31/2023
SGEN	3,636	$736	03/31/2023
Pathstone Family Office LLC	3,597	$728	03/31/2023
SGEN	3,597	$728	03/31/2023
Dana Investment Advisors Inc.	3,572	$723	03/31/2023
SGEN	3,572	$723	03/31/2023
Nisa Investment Advisors LLC	3,435	$695	03/31/2023
SGEN	3,435	$695	03/31/2023
Alberta Investment Management Corp	3,400	$688	03/31/2023
SGEN	3,400	$688	03/31/2023
Pinnacle Wealth Management Advisory Group LLC	3,390	$686	03/31/2023
SGEN	3,390	$686	03/31/2023
Vestcor Inc	3,264	$661	03/31/2023
SGEN	3,264	$661	03/31/2023
Beacon Pointe Advisors LLC	3,227	$653	03/31/2023
SGEN	3,227	$653	03/31/2023
First Manhattan Co.	3,200	$648	03/31/2023
SGEN	3,200	$648	03/31/2023
Whittier Trust Co. of Nevada Inc.	3,123	$632	03/31/2023
SGEN	3,123	$632	03/31/2023
Stonnington Group LLC	3,060	$631	03/31/2023
SGEN	3,060	$631	03/31/2023
D.A. Davidson & CO.	3,084	$624	03/31/2023
SGEN	3,084	$624	03/31/2023
Institute for Wealth Management LLC.	3,043	$616	03/31/2023
SGEN	3,043	$616	03/31/2023
Seaport Global Advisors LLC	3,037	$615	03/31/2023
SGEN	3,037	$615	03/31/2023
First Republic Investment Management Inc.	2,950	$597	03/31/2023
SGEN	2,950	$597	03/31/2023
Metis Global Partners LLC	2,946	$596	03/31/2023
SGEN	2,946	$596	03/31/2023
Northeast Financial Consultants Inc	2,900	$587	03/31/2023
SGEN	2,900	$587	03/31/2023
Kestra Advisory Services LLC	2,837	$574	03/31/2023
SGEN	2,837	$574	03/31/2023
RMB Capital Management LLC	2,814	$570	03/31/2023
SGEN	2,814	$570	03/31/2023
Tocqueville Asset Management L.P.	2,808	$569	03/31/2023
SGEN	2,808	$569	03/31/2023
Nelson Van Denburg & Campbell Wealth Management Group LLC	2,800	$567	03/31/2023
SGEN	2,800	$567	03/31/2023
Flow State Investments L.P.		$567	03/31/2023
Call	2,800	$567	03/31/2023
Howe & Rusling Inc.	2,768	$560	03/31/2023
SGEN	2,768	$560	03/31/2023
Shell Asset Management Co.	2,702	$547	03/31/2023
SGEN	2,702	$547	03/31/2023
Wetherby Asset Management Inc.	2,646	$536	03/31/2023
SGEN	2,646	$536	03/31/2023
Mercer Global Advisors Inc. ADV	2,592	$525	03/31/2023
SGEN	2,592	$525	03/31/2023
China Universal Asset Management Co. Ltd.	2,587	$524	03/31/2023
SGEN	2,587	$524	03/31/2023
Green Alpha Advisors LLC	2,576	$522	03/31/2023
SGEN	2,576	$522	03/31/2023
Winthrop Advisory Group LLC	2,568	$520	03/31/2023
SGEN	2,568	$520	03/31/2023
BI Asset Management Fondsmaeglerselskab A S	2,566	$520	03/31/2023
SGEN	2,566	$520	03/31/2023
Ballentine Partners LLC	2,544	$515	03/31/2023
SGEN	2,544	$515	03/31/2023
Harbor Investment Advisory LLC	2,500	$506	03/31/2023
SGEN	2,500	$506	03/31/2023
Keebeck Alpha LP	2,494	$505	03/31/2023
SGEN	2,494	$505	03/31/2023
Norinchukin Bank The	2,483	$503	03/31/2023
SGEN	2,483	$503	03/31/2023
First City Capital Management Inc.	2,470	$494	03/31/2023
SGEN	2,470	$494	03/31/2023
Levy Wealth Management Group LLC	2,430	$492	03/31/2023
SGEN	2,430	$492	03/31/2023
National Wealth Management Group LLC	2,414	$480	03/31/2023
SGEN	2,414	$480	03/31/2023
Lake Street Financial LLC	2,360	$478	03/31/2023
SGEN	2,360	$478	03/31/2023
Vinva Investment Management Ltd	2,340	$475	03/31/2023
SGEN	2,340	$475	03/31/2023
Virtus ETF Advisers LLC	2,332	$472	03/31/2023
SGEN	2,332	$472	03/31/2023
Virtu Financial LLC	2,274	$460	03/31/2023
SGEN	2,274	$460	03/31/2023
Cibc World Markets Corp	2,241	$454	03/31/2023
SGEN	2,241	$454	03/31/2023
Foundry Partners LLC	2,224	$450	03/31/2023
SGEN	2,224	$450	03/31/2023
CI Investments Inc.	2,199	$445	03/31/2023
SGEN	2,199	$445	03/31/2023
Circle Wealth Management LLC	2,200	$445	03/31/2023
SGEN	2,200	$445	03/31/2023
Mint Tower Capital Management B.V.	2,200	$445	03/31/2023
SGEN	2,200	$445	03/31/2023
Badgley Phelps Wealth Managers LLC	2,144	$434	03/31/2023
SGEN	2,144	$434	03/31/2023
STF Management LP	2,127	$431	03/31/2023
SGEN	2,127	$431	03/31/2023
Great Lakes Advisors LLC	2,124	$430	03/31/2023
SGEN	2,124	$430	03/31/2023
Cambridge Investment Research Advisors Inc.	2,103	$426	03/31/2023
SGEN	2,103	$426	03/31/2023
Toroso Investments LLC	2,085	$422	03/31/2023
SGEN	2,085	$422	03/31/2023
Signaturefd LLC	2,067	$419	03/31/2023
SGEN	2,067	$419	03/31/2023
Q3 Asset Management	2,005	$406	03/31/2023
SGEN	2,005	$406	03/31/2023
Leavell Investment Management Inc.	2,000	$405	03/31/2023
SGEN	2,000	$405	03/31/2023
Silvercrest Asset Management Group LLC	2,000	$405	03/31/2023
SGEN	2,000	$405	03/31/2023
Manchester Capital Management LLC	2,000	$405	03/31/2023
SGEN	2,000	$405	03/31/2023
Lumina Fund Management LLC	2,000	$405	03/31/2023
SGEN	2,000	$405	03/31/2023
PenderFund Capital Management Ltd.	1,450	$397	03/31/2023
SGEN	1,450	$397	03/31/2023
Snowden Capital Advisors LLC	1,931	$391	03/31/2023
SGEN	1,931	$391	03/31/2023
Pictet & Cie Europe SA	1,900	$385	03/31/2023
SGEN	1,900	$385	03/31/2023
Vestmark Advisory Solutions Inc.	1,903	$385	03/31/2023
SGEN	1,903	$385	03/31/2023
Ontario Teachers Pension Plan Board	1,862	$377	03/31/2023
SGEN	1,862	$377	03/31/2023
Two Sigma Securities LLC		$364	03/31/2023
Call	1,800	$364	03/31/2023
Ieq Capital LLC	1,791	$363	03/31/2023
SGEN	1,791	$363	03/31/2023
ArrowMark Colorado Holdings LLC	1,750	$354	03/31/2023
SGEN	1,750	$354	03/31/2023
Palisade Capital Management LLC NJ	1,734	$351	03/31/2023
SGEN	1,734	$351	03/31/2023
West Family Investments Inc.	1,685	$341	03/31/2023
SGEN	1,685	$341	03/31/2023
Fund Management at Engine No. 1 LLC	1,665	$337	03/31/2023
SGEN	1,665	$337	03/31/2023
RMR Wealth Builders	1,656	$335	03/31/2023
SGEN	1,656	$335	03/31/2023
Regions Financial Corp	1,622	$328	03/31/2023
SGEN	1,622	$328	03/31/2023
Greenland Capital Management LP	1,600	$324	03/31/2023
SGEN	1,600	$324	03/31/2023
Yousif Capital Management LLC	1,588	$322	03/31/2023
SGEN	1,588	$322	03/31/2023
Connecticut Wealth Management LLC	1,583	$321	03/31/2023
SGEN	1,583	$321	03/31/2023
Sequoia Financial Advisors LLC	1,552	$314	03/31/2023
SGEN	1,552	$314	03/31/2023
Emerald Advisers LLC	1,509	$306	03/31/2023
SGEN	1,509	$306	03/31/2023
Advisory Services Network LLC	1,508	$305	03/31/2023
SGEN	1,508	$305	03/31/2023
Landscape Capital Management L.L.C.	1,500	$304	03/31/2023
SGEN	1,500	$304	03/31/2023
High Net Worth Advisory Group LLC	1,500	$304	03/31/2023
SGEN	1,500	$304	03/31/2023
Balentine LLC	1,496	$303	03/31/2023
SGEN	1,496	$303	03/31/2023
Cigna Investments Inc. New	1,483	$300	03/31/2023
SGEN	1,483	$300	03/31/2023
Atria Wealth Solutions Inc.	1,482	$300	03/31/2023
SGEN	1,482	$300	03/31/2023
Brighton Jones LLC	1,455	$295	03/31/2023
SGEN	1,455	$295	03/31/2023
Garde Capital Inc.	1,450	$294	03/31/2023
SGEN	1,450	$294	03/31/2023
Teza Capital Management LLC	1,452	$294	03/31/2023
SGEN	1,452	$294	03/31/2023
Bridgefront Capital LLC	1,408	$285	03/31/2023
SGEN	1,408	$285	03/31/2023
Dynamic Technology Lab Private Ltd	1,405	$284	03/31/2023
SGEN	1,405	$284	03/31/2023
Resources Investment Advisors LLC.	1,390	$281	03/31/2023
SGEN	1,390	$281	03/31/2023
Peapack Gladstone Financial Corp	1,375	$278	03/31/2023
SGEN	1,375	$278	03/31/2023
Bank Julius Baer & Co. Ltd Zurich	1,375	$278	03/31/2023
SGEN	1,375	$278	03/31/2023
EverSource Wealth Advisors LLC	1,338	$271	03/31/2023
SGEN	1,338	$271	03/31/2023
Headlands Technologies LLC	1,321	$267	03/31/2023
SGEN	1,321	$267	03/31/2023
Pacific Global Investment Management CO	1,300	$263	03/31/2023
SGEN	1,300	$263	03/31/2023
Centiva Capital LP		$263	03/31/2023
SGEN	26,299	$5,325	03/31/2023
Put	25,000	$5,062	03/31/2023
Sagefield Capital LP	1,300	$263	03/31/2023
SGEN	1,300	$263	03/31/2023
Edgestream Partners L.P.	1,273	$258	03/31/2023
SGEN	1,273	$258	03/31/2023
Capital Advisory Group Advisory Services LLC	1,265	$256	03/31/2023
SGEN	1,265	$256	03/31/2023
Waldron Private Wealth LLC	1,263	$255	03/31/2023
SGEN	1,263	$255	03/31/2023
Ellevest Inc.	1,251	$253	03/31/2023
SGEN	1,251	$253	03/31/2023
Fiduciary Trust Co.	1,244	$252	03/31/2023
SGEN	1,244	$252	03/31/2023
Crossmark Global Holdings Inc.	1,238	$250	03/31/2023
SGEN	1,238	$250	03/31/2023
SageView Advisory Group LLC	1,236	$250	03/31/2023
SGEN	1,236	$250	03/31/2023
Schechter Investment Advisors LLC	1,232	$249	03/31/2023
SGEN	1,232	$249	03/31/2023
Strategic Blueprint LLC	1,209	$245	03/31/2023
SGEN	1,209	$245	03/31/2023
Nia Impact Advisors LLC	1,201	$243	03/31/2023
SGEN	1,201	$243	03/31/2023
	1,196	$242	03/31/2023
SGEN	1,196	$242	03/31/2023
Rockefeller Capital Management L.P.	1,203	$242	03/31/2023
SGEN	1,203	$242	03/31/2023
TIAA FSB	1,171	$237	03/31/2023
SGEN	1,171	$237	03/31/2023
Cedar Brook Financial Partners LLC	1,164	$236	03/31/2023
SGEN	1,164	$236	03/31/2023
Symmetry Partners LLC	1,151	$233	03/31/2023
SGEN	1,151	$233	03/31/2023
Keel Point LLC	1,130	$229	03/31/2023
SGEN	1,130	$229	03/31/2023
IFP Advisors Inc	1,086	$218	03/31/2023
SGEN	1,086	$218	03/31/2023
Raymond James Trust N.A.	1,074	$217	03/31/2023
SGEN	1,074	$217	03/31/2023
Eqis Capital Management Inc.	1,064	$216	03/31/2023
SGEN	1,064	$216	03/31/2023
Hoylecohen LLC	1,056	$214	03/31/2023
SGEN	1,056	$214	03/31/2023
Investment Advisory Group LLC	1,050	$213	03/31/2023
SGEN	1,050	$213	03/31/2023
Advisor Partners II LLC	1,051	$213	03/31/2023
SGEN	1,051	$213	03/31/2023
Forum Financial Management LP	1,048	$212	03/31/2023
SGEN	1,048	$212	03/31/2023
Greenleaf Trust	1,030	$209	03/31/2023
SGEN	1,030	$209	03/31/2023
Ossiam	1,018	$206	03/31/2023
SGEN	1,018	$206	03/31/2023
Magnus Financial Group LLC	1,003	$203	03/31/2023
SGEN	1,003	$203	03/31/2023
Financial Advisory Service Inc.	1,000	$202	03/31/2023
SGEN	1,000	$202	03/31/2023
Mirador Capital Partners LP	1,000	$202	03/31/2023
SGEN	1,000	$202	03/31/2023
Wealthcare Advisory Partners LLC	998	$202	03/31/2023
SGEN	998	$202	03/31/2023
Machina Capital S.A.S.	1,000	$202	03/31/2023
SGEN	1,000	$202	03/31/2023
Williams Jones Wealth Management LLC.	1,000	$202	03/31/2023
SGEN	1,000	$202	03/31/2023
Dark Forest Capital Management LP	926	$187	03/31/2023
SGEN	926	$187	03/31/2023
Banque Cantonale Vaudoise	699	$142	03/31/2023
SGEN	699	$142	03/31/2023
Steward Partners Investment Advisory LLC	636	$129	03/31/2023
SGEN	636	$129	03/31/2023
Clearstead Advisors LLC	574	$116	03/31/2023
SGEN	574	$116	03/31/2023
Alpha Paradigm Partners LLC	851	$109	12/31/2022
SGEN	851	$109	12/31/2022
Harbour Investments Inc.	524	$106	03/31/2023
SGEN	524	$106	03/31/2023
Itau Unibanco Holding S.A.	515	$104	03/31/2023
SGEN	515	$104	03/31/2023
Brown Brothers Harriman & Co.	508	$103	03/31/2023
SGEN	508	$103	03/31/2023
Cutler Group LP	500	$101	03/31/2023
SGEN	500	$101	03/31/2023
Harvest Fund Management Co. Ltd	489	$99	03/31/2023
SGEN	489	$99	03/31/2023
Quadrant Capital Group LLC	435	$88	03/31/2023
SGEN	435	$88	03/31/2023
Covestor Ltd	434	$88	03/31/2023
SGEN	434	$88	03/31/2023
Global Retirement Partners LLC	382	$76	03/31/2023
SGEN	382	$76	03/31/2023
WealthPLAN Partners LLC	345	$70	03/31/2023
SGEN	345	$70	03/31/2023
True Wealth Design LLC	302	$61	03/31/2023
SGEN	302	$61	03/31/2023
Proficio Capital Partners LLC	51,225	$51	03/31/2023
SGEN	51,225	$51	03/31/2023
Achmea Investment Management B.V.	232	$47	03/31/2023
SGEN	232	$47	03/31/2023
BerganKDV Wealth Management LLC	225	$46	03/31/2023
SGEN	225	$46	03/31/2023
Bessemer Group Inc.	224	$45	03/31/2023
SGEN	224	$45	03/31/2023
Spire Wealth Management	224	$45	03/31/2023
SGEN	224	$45	03/31/2023
First Horizon Advisors Inc.	205	$42	03/31/2023
SGEN	205	$42	03/31/2023
Endurance Wealth Management Inc.	200	$40	03/31/2023
SGEN	200	$40	03/31/2023
Livforsakringsbolaget Skandia Omsesidigt	200	$40	03/31/2023
SGEN	200	$40	03/31/2023
Lindbrook Capital LLC	196	$40	03/31/2023
SGEN	196	$40	03/31/2023
Glassman Wealth Services	182	$37	03/31/2023
SGEN	182	$37	03/31/2023
Parallel Advisors LLC	181	$37	03/31/2023
SGEN	181	$37	03/31/2023
First Command Bank	150	$30	03/31/2023
SGEN	150	$30	03/31/2023
First Command Financial Services Inc.	150	$30	03/31/2023
SGEN	150	$30	03/31/2023
Valley National Advisers Inc.	142	$29	03/31/2023
SGEN	142	$29	03/31/2023
UBS Oconnor LLC	1,429	$29	03/31/2023
SGEN	1,429	$29	03/31/2023
Riverview Trust Co	131	$27	03/31/2023
SGEN	131	$27	03/31/2023
Baillie Gifford & Co.	128	$26	03/31/2023
SGEN	128	$26	03/31/2023
GWM Advisors LLC	130	$26	03/31/2023
SGEN	130	$26	03/31/2023
KB Financial Partners LLC	125	$25	03/31/2023
SGEN	125	$25	03/31/2023
James Investment Research Inc.	108	$22	03/31/2023
SGEN	108	$22	03/31/2023
Catalyst Capital Advisors LLC	109	$22	03/31/2023
SGEN	109	$22	03/31/2023
Belpointe Asset Management LLC	110	$22	03/31/2023
SGEN	110	$22	03/31/2023
TFC Financial Management	108	$22	03/31/2023
SGEN	108	$22	03/31/2023
CENTRAL TRUST Co	100	$20	03/31/2023
SGEN	100	$20	03/31/2023
Mark Sheptoff Financial Planning LLC	100	$20	03/31/2023
SGEN	100	$20	03/31/2023
Bbjs Financial Advisors LLC	100	$20	03/31/2023
SGEN	100	$20	03/31/2023
Smithfield Trust Co.	95	$19	03/31/2023
SGEN	95	$19	03/31/2023
Princeton Global Asset Management LLC	93	$19	03/31/2023
SGEN	93	$19	03/31/2023
Ronald Blue Trust Inc.	150	$19	03/31/2023
SGEN	150	$19	03/31/2023
Park Place Capital Corp	94	$19	03/31/2023
SGEN	94	$19	03/31/2023
Lazard Asset Management LLC	92	$18	03/31/2023
SGEN	92	$18	03/31/2023
Sunbelt Securities Inc.	91	$18	03/31/2023
SGEN	91	$18	03/31/2023
Fifth Third Bancorp	78	$16	03/31/2023
SGEN	78	$16	03/31/2023
Financial Avengers Inc.	80	$16	03/31/2023
SGEN	80	$16	03/31/2023
Earnest Partners LLC	71	$14	03/31/2023
SGEN	71	$14	03/31/2023
Private Trust Co. NA	70	$14	03/31/2023
SGEN	70	$14	03/31/2023
Prestige Wealth Management Group LLC	64	$13	03/31/2023
SGEN	64	$13	03/31/2023
Bell Investment Advisors Inc	58	$12	03/31/2023
SGEN	58	$12	03/31/2023
Kayne Anderson Rudnick Investment Management LLC	55	$11	03/31/2023
SGEN	55	$11	03/31/2023
Allworth Financial LP	54	$11	03/31/2023
SGEN	54	$11	03/31/2023
Riggs Asset Managment Co. Inc.	50	$10	03/31/2023
SGEN	50	$10	03/31/2023
Parkside Financial Bank & Trust	46	$9	03/31/2023
SGEN	46	$9	03/31/2023
Venturi Wealth Management LLC	42	$9	03/31/2023
SGEN	42	$9	03/31/2023
McIlrath & Eck LLC	45	$9	03/31/2023
SGEN	45	$9	03/31/2023
Quent Capital LLC	42	$9	03/31/2023
SGEN	42	$9	03/31/2023
JFS Wealth Advisors LLC	38	$8	03/31/2023
SGEN	38	$8	03/31/2023
Zions Bancorporation N.A.	38	$8	03/31/2023
SGEN	38	$8	03/31/2023
Accel Wealth Management	40	$8	03/31/2023
SGEN	40	$8	03/31/2023
UMB Bank N A MO	37	$7	03/31/2023
SGEN	37	$7	03/31/2023
Benjamin F. Edwards & Company Inc.	36	$7	03/31/2023
SGEN	36	$7	03/31/2023
JGP Global Gestao de Recursos Ltda.	160,000	$7	03/31/2023
SGEN	160,000	$7	03/31/2023
NewSquare Capital LLC	34	$7	03/31/2023
SGEN	34	$7	03/31/2023
Ridgewood Investments LLC	34	$7	03/31/2023
SGEN	34	$7	03/31/2023
Centerpoint Advisors LLC	35	$7	03/31/2023
SGEN	35	$7	03/31/2023
TCI Wealth Advisors Inc.	31	$6	03/31/2023
SGEN	31	$6	03/31/2023
International Assets Investment Management LLC	28	$6	03/31/2023
SGEN	28	$6	03/31/2023
AdvisorNet Financial Inc	23	$5	03/31/2023
SGEN	23	$5	03/31/2023
Crewe Advisors LLC	26	$5	03/31/2023
SGEN	26	$5	03/31/2023
Steward Financial Group LLC	28	$5	03/31/2023
SGEN	28	$5	03/31/2023
Sargent Bickham Lagudis LLC	41	$5	12/31/2022
SGEN	41	$5	12/31/2022
CoreCap Advisors LLC	39	$5	12/31/2022
SGEN	39	$5	12/31/2022
Huntington National Bank	18	$4	03/31/2023
SGEN	18	$4	03/31/2023
Salem Investment Counselors Inc.	18	$4	03/31/2023
SGEN	18	$4	03/31/2023
Thomas J. Herzfeld Advisors Inc.	22	$4	03/31/2023
SGEN	22	$4	03/31/2023
Capital Advisors Ltd. LLC	19	$4	03/31/2023
SGEN	19	$4	03/31/2023
Wolff Wiese Magana LLC	20	$4	03/31/2023
SGEN	20	$4	03/31/2023
Eagle Bay Advisors LLC	20	$4	03/31/2023
SGEN	20	$4	03/31/2023
Massmutual Trust Co. FSB ADV	17	$3	03/31/2023
SGEN	17	$3	03/31/2023
Northwest Investment Counselors LLC	17	$3	03/31/2023
SGEN	17	$3	03/31/2023
Exchange Traded Concepts LLC	14	$3	03/31/2023
SGEN	14	$3	03/31/2023
Rise Advisors LLC	15	$3	03/31/2023
SGEN	15	$3	03/31/2023
Penserra Capital Management LLC	10	$2	03/31/2023
SGEN	10	$2	03/31/2023
Disciplined Investments LLC	8	$2	03/31/2023
SGEN	8	$2	03/31/2023
SJS Investment Consulting Inc.	10	$2	03/31/2023
SGEN	10	$2	03/31/2023
Schubert & Co	12	$2	03/31/2023
SGEN	12	$2	03/31/2023
Red Tortoise LLC	11	$2	03/31/2023
SGEN	11	$2	03/31/2023
BOKF NA	4	$1	03/31/2023
SGEN	4	$1	03/31/2023
ClariVest Asset Management LLC	6	$1	03/31/2023
SGEN	6	$1	03/31/2023
Baker Avenue Asset Management LP	4	$1	03/31/2023
SGEN	4	$1	03/31/2023
Jackson Grant Investment Advisers Inc.	5	$1	03/31/2023
SGEN	5	$1	03/31/2023
Versant Capital Management Inc	5	$1	03/31/2023
SGEN	5	$1	03/31/2023
Rosenberg Matthew Hamilton	6	$1	03/31/2023
SGEN	6	$1	03/31/2023
Proequities Inc.		$0	03/31/2023
Put	0	$0	03/31/2023
Call	0	$0	03/31/2023
SGEN	2	$0	03/31/2023
Moore Capital Management LP		$0	03/31/2023
Put	20,000	$4,049	03/31/2023
SGEN	20,000	$4,049	03/31/2023
JJJ Advisors Inc.	2	$0	03/31/2023
SGEN	2	$0	03/31/2023
25 LLC	2	$0	03/31/2023
SGEN	2	$0	03/31/2023
Bluefin Capital Management LLC		$-13	03/31/2023
Put	120,100	$13	03/31/2023
DRW Securities LLC		$-223	03/31/2023
Put	2,900	$587	03/31/2023
SGEN	1,800	$364	03/31/2023
HAP Trading LLC		$-226	03/31/2023
Put	78,400	$226	03/31/2023
Harvest Management LLC		$-608	03/31/2023
Put	10,000	$2,025	03/31/2023
SGEN	7,000	$1,417	03/31/2023
Parallax Volatility Advisers L.P.		$-1,235	03/31/2023
Put	63,300	$12,816	03/31/2023
Call	57,200	$11,581	03/31/2023
Maven Securities LTD		$-6,459	03/31/2023
Put	52,200	$10,569	03/31/2023
Call	17,800	$3,604	03/31/2023
SGEN	2,500	$506	03/31/2023
TIG Advisors LLC		$-8,544	03/31/2023
Put	42,200	$8,544	03/31/2023
Caption Management LLC		$-30,370	03/31/2023
Put	150,000	$30,370	03/31/2023
Jefferies Financial Group Inc.		$-31,636	03/31/2023
Put	239,500	$48,492	03/31/2023
SGEN	53,250	$10,782	03/31/2023
Call	30,000	$6,074	03/31/2023
Deep Track Capital LP	217,800	$-44,098	03/31/2023
Put	217,800	$44,098	03/31/2023