HoldingsChannel.com
Funds Holding QURE
HolderAmountPosition Size
($ in 1000's)		 As of
FMR LLC3,688,791$220,036 03/31/2019
     QURE3,688,791$220,036 03/31/2019
Nantahala Capital Management LLC $162,170 03/31/2019
     QURE1,518,690$90,590 03/31/2019
     Call1,200,000$71,580 03/31/2019
Consonance Capital Management LP1,985,460$118,433 03/31/2019
     QURE1,985,460$118,433 03/31/2019
OppenheimerFunds Inc.1,817,534$108,416 03/31/2019
     QURE1,817,534$108,416 03/31/2019
Redmile Group LLC1,307,522$77,994 03/31/2019
     QURE1,307,522$77,994 03/31/2019
Federated Investors Inc. PA1,272,228$75,888 03/31/2019
     QURE1,272,228$75,888 03/31/2019
Boxer Capital LLC950,000$56,668 03/31/2019
     QURE950,000$56,668 03/31/2019
683 Capital Management LLC750,000$44,738 03/31/2019
     QURE750,000$44,738 03/31/2019
Macquarie Group Ltd.680,000$40,562 03/31/2019
     QURE680,000$40,562 03/31/2019
Susquehanna International Group LLP $39,039 03/31/2019
     Call455,500$27,171 03/31/2019
     QURE263,257$15,703 03/31/2019
     Put64,300$3,835 03/31/2019
Lord Abbett & CO. LLC647,626$38,631 03/31/2019
     QURE647,626$38,631 03/31/2019
Baker BROS. Advisors LP605,000$36,088 03/31/2019
     QURE605,000$36,088 03/31/2019
Franklin Resources Inc.556,000$33,165 03/31/2019
     QURE556,000$33,165 03/31/2019
Eventide Asset Management LLC538,700$32,133 03/31/2019
     QURE538,700$32,133 03/31/2019
BlackRock Inc.452,730$27,005 03/31/2019
     QURE452,730$27,005 03/31/2019
JPMorgan Chase & Co. $26,316 03/31/2019
     QURE414,980$24,753 03/31/2019
     Call35,300$2,106 03/31/2019
     Put9,100$543 03/31/2019
Millennium Management LLC $25,271 03/31/2019
     QURE307,640$18,351 03/31/2019
     Call141,000$8,411 03/31/2019
     Put25,000$1,491 03/31/2019
FIL Ltd419,392$25,017 03/31/2019
     QURE419,392$25,017 03/31/2019
Partner Fund Management L.P.416,862$24,866 03/31/2019
     QURE416,862$24,866 03/31/2019
Aquilo Capital Management LLC364,596$21,748 03/31/2019
     QURE364,596$21,748 03/31/2019
Adage Capital Partners GP L.L.C.325,000$19,386 03/31/2019
     QURE325,000$19,386 03/31/2019
Price T Rowe Associates Inc. MD299,308$17,854 03/31/2019
     QURE299,308$17,854 03/31/2019
Sphera Funds Management LTD. $16,544 03/31/2019
     Call200,000$11,930 03/31/2019
     QURE77,349$4,614 03/31/2019
Perceptive Advisors LLC231,820$13,828 03/31/2019
     QURE231,820$13,828 03/31/2019
Opaleye Management Inc.205,000$12,228 03/31/2019
     QURE205,000$12,228 03/31/2019
Vivo Capital LLC180,336$10,757 03/31/2019
     QURE180,336$10,757 03/31/2019
RTW Investments LP154,058$9,190 03/31/2019
     QURE154,058$9,190 03/31/2019
Henry James International Management Inc.105,844$8,272 06/30/2019
     QURE105,844$8,272 06/30/2019
Citadel Advisors LLC $7,512 03/31/2019
     QURE100,334$5,985 03/31/2019
     Call71,900$4,289 03/31/2019
     Put46,300$2,762 03/31/2019
D. E. Shaw & Co. Inc.122,660$7,317 03/31/2019
     QURE122,660$7,317 03/31/2019
Alps Advisors Inc.89,224$5,322 03/31/2019
     QURE89,224$5,322 03/31/2019
Ameriprise Financial Inc.89,047$5,311 03/31/2019
     QURE89,047$5,311 03/31/2019
Nicholas Investment Partners LP87,702$5,231 03/31/2019
     QURE87,702$5,231 03/31/2019
Allianz Asset Management GmbH78,945$4,709 03/31/2019
     QURE78,945$4,709 03/31/2019
Boothbay Fund Management LLC $4,646 03/31/2019
     Call619$3,692 03/31/2019
     QURE16,000$954 03/31/2019
Vanguard Group Inc.75,434$4,500 03/31/2019
     QURE75,434$4,500 03/31/2019
Renaissance Technologies LLC74,400$4,438 03/31/2019
     QURE74,400$4,438 03/31/2019
Deutsche Bank AG70,019$4,175 03/31/2019
     QURE70,019$4,175 03/31/2019
Goldman Sachs Group Inc.69,253$4,131 03/31/2019
     QURE69,253$4,131 03/31/2019
Morgan Stanley64,622$3,855 03/31/2019
     QURE64,622$3,855 03/31/2019
WS Management Lllp60,304$3,597 03/31/2019
     QURE60,304$3,597 03/31/2019
Invesco Ltd.60,130$3,587 03/31/2019
     QURE60,130$3,587 03/31/2019
Royce & Associates LP60,000$3,579 03/31/2019
     QURE60,000$3,579 03/31/2019
Two Sigma Investments LP55,180$3,291 03/31/2019
     QURE55,180$3,291 03/31/2019
P.A.W. Capital Corp55,000$3,281 03/31/2019
     QURE55,000$3,281 03/31/2019
Senvest Management LLC54,625$3,258 03/31/2019
     QURE54,625$3,258 03/31/2019
Sanders Morris Harris LLC40,100$3,084 06/30/2019
     QURE40,100$3,084 06/30/2019
State Street Corp47,799$2,851 03/31/2019
     QURE47,799$2,851 03/31/2019
California Public Employees Retirement System47,686$2,844 03/31/2019
     QURE47,686$2,844 03/31/2019
Parallax Volatility Advisers L.P. $2,641 03/31/2019
     Call40,000$2,386 03/31/2019
     QURE4,279$255 03/31/2019
Swiss National Bank44,200$2,637 03/31/2019
     QURE44,200$2,637 03/31/2019
HAP Trading LLC $2,457 03/31/2019
     Call101,600$2,457 03/31/2019
Northern Trust Corp40,735$2,429 03/31/2019
     QURE40,735$2,429 03/31/2019
Nexthera Capital LP38,800$2,314 03/31/2019
     QURE38,800$2,314 03/31/2019
Bellevue Group AG38,300$2,285 03/31/2019
     QURE38,300$2,285 03/31/2019
Geode Capital Management LLC37,989$2,266 03/31/2019
     QURE37,989$2,266 03/31/2019
Bank of New York Mellon Corp36,741$2,191 03/31/2019
     QURE36,741$2,191 03/31/2019
Eqis Capital Management Inc.27,126$2,120 06/30/2019
     QURE27,126$2,120 06/30/2019
Graticule Asia Macro Advisors LLC35,159$2,097 03/31/2019
     QURE35,159$2,097 03/31/2019
HBK Investments L P33,801$2,016 03/31/2019
     QURE33,801$2,016 03/31/2019
Trexquant Investment LP32,772$1,955 03/31/2019
     QURE32,772$1,955 03/31/2019
Group One Trading L.P. $1,904 03/31/2019
     Call35,400$2,112 03/31/2019
     Put5,600$334 03/31/2019
     QURE2,116$126 03/31/2019
Man Group plc31,004$1,849 03/31/2019
     QURE31,004$1,849 03/31/2019
Envestnet Asset Management Inc.26,168$1,561 03/31/2019
     QURE26,168$1,561 03/31/2019
Squarepoint Ops LLC23,526$1,403 03/31/2019
     QURE23,526$1,403 03/31/2019
Caption Management LLC $1,194 03/31/2019
     Call20,000$1,194 03/31/2019
Tekla Capital Management LLC19,751$1,178 03/31/2019
     QURE19,751$1,178 03/31/2019
Credit Suisse AG19,142$1,141 03/31/2019
     QURE19,142$1,141 03/31/2019
Moore Capital Management LP17,256$1,029 03/31/2019
     QURE17,256$1,029 03/31/2019
Wells Fargo & Company MN $967 03/31/2019
     QURE16,239$969 03/31/2019
     Put1,000$2 03/31/2019
Doheny Asset Management CA15,145$903 03/31/2019
     QURE15,145$903 03/31/2019
UBS Asset Management Americas Inc.14,806$883 03/31/2019
     QURE14,806$883 03/31/2019
Bank of America Corp DE14,423$860 03/31/2019
     QURE14,423$860 03/31/2019
Moody Aldrich Partners LLC14,250$850 03/31/2019
     QURE14,250$850 03/31/2019
Opus Point Partners Management LLC14,215$848 03/31/2019
     QURE14,215$848 03/31/2019
ProShare Advisors LLC12,782$762 03/31/2019
     QURE12,782$762 03/31/2019
Voloridge Investment Management LLC12,713$758 03/31/2019
     QURE12,713$758 03/31/2019
DRW Securities LLC12,300$734 03/31/2019
     QURE12,300$734 03/31/2019
Citigroup Inc. $683 03/31/2019
     Call11,700$698 03/31/2019
     Put3,600$215 03/31/2019
     QURE3,349$200 03/31/2019
Barclays PLC10,040$598 03/31/2019
     QURE10,040$598 03/31/2019
Virtus ETF Advisers LLC9,543$569 03/31/2019
     QURE9,543$569 03/31/2019
Advisor Group Inc.8,939$533 03/31/2019
     QURE8,939$533 03/31/2019
DekaBank Deutsche Girozentrale12,300$520 03/31/2019
     QURE12,300$520 03/31/2019
Atria Investments LLC8,677$518 03/31/2019
     QURE8,677$518 03/31/2019
Assenagon Asset Management S.A.8,345$498 03/31/2019
     QURE8,345$498 03/31/2019
Balyasny Asset Management LLC8,123$485 03/31/2019
     QURE8,123$485 03/31/2019
Carmignac Gestion8,137$485 03/31/2019
     QURE8,137$485 03/31/2019
Virtu Financial LLC8,001$477 03/31/2019
     QURE8,001$477 03/31/2019
A.R.T. Advisors LLC7,446$444 03/31/2019
     QURE7,446$444 03/31/2019
Pura Vida Investments LLC7,370$440 03/31/2019
     QURE7,370$440 03/31/2019
Two Sigma Advisers LP7,100$424 03/31/2019
     QURE7,100$424 03/31/2019
Walleye Trading LLC $378 03/31/2019
     Call6,700$400 03/31/2019
     Put900$54 03/31/2019
     QURE536$32 03/31/2019
Cutler Group LP $354 03/31/2019
     QURE3,900$232 03/31/2019
     Call9,700$122 03/31/2019
     Put2,200$0 03/31/2019
Principal Financial Group Inc.5,801$346 03/31/2019
     QURE5,801$346 03/31/2019
Jane Street Group LLC5,561$332 03/31/2019
     QURE5,561$332 03/31/2019
Royal Bank of Canada5,539$331 03/31/2019
     QURE5,539$331 03/31/2019
Xact Kapitalforvaltning AB4,200$328 06/30/2019
     QURE4,200$328 06/30/2019
Mitsubishi UFJ Kokusai Asset Management Co. Ltd.5,045$301 03/31/2019
     QURE5,045$301 03/31/2019
New York State Common Retirement Fund4,960$296 03/31/2019
     QURE4,960$296 03/31/2019
Gagnon Securities LLC4,594$274 03/31/2019
     QURE4,594$274 03/31/2019
Cowen Inc. $268 03/31/2019
     QURE4,000$239 03/31/2019
     Call23,500$29 03/31/2019
Parametric Portfolio Associates LLC4,459$266 03/31/2019
     QURE4,459$266 03/31/2019
Dynamic Technology Lab Private Ltd4,300$256 03/31/2019
     QURE4,300$256 03/31/2019
Campbell & CO Investment Adviser LLC3,160$247 06/30/2019
     QURE3,160$247 06/30/2019
First Citizens Bank & Trust Co.2,694$211 06/30/2019
     QURE2,694$211 06/30/2019
Partner Investment Management L.P.3,411$203 03/31/2019
     QURE3,411$203 03/31/2019
Financial Gravity Wealth Inc.2,549$153 03/31/2019
     QURE2,549$153 03/31/2019
Simplex Trading LLC $144 03/31/2019
     Call38$226 03/31/2019
     Put24$143 03/31/2019
     QURE1,030$61 03/31/2019
Wolverine Asset Management LLC $113 03/31/2019
     Call1,900$113 03/31/2019
UBS Group AG1,866$112 03/31/2019
     QURE1,866$112 03/31/2019
Zurcher Kantonalbank Zurich Cantonalbank 1,629$97 03/31/2019
     QURE1,629$97 03/31/2019
Walleye Trading Advisors LLC $96 03/31/2019
     Call2,300$137 03/31/2019
     Put1,900$113 03/31/2019
     QURE1,205$72 03/31/2019
Tower Research Capital LLC TRC 1,312$78 03/31/2019
     QURE1,312$78 03/31/2019
Legal & General Group Plc965$58 03/31/2019
     QURE965$58 03/31/2019
BlueMountain Capital Management LLC968$58 03/31/2019
     QURE968$58 03/31/2019
Glenmede Trust Co. NA950$56 03/31/2019
     QURE950$56 03/31/2019
SEI Investments Co595$35 03/31/2019
     QURE595$35 03/31/2019
Pearl River Capital LLC544$32 03/31/2019
     QURE544$32 03/31/2019
Sterling Investment Advisors Ltd.500$30 03/31/2019
     QURE500$30 03/31/2019
Kore Private Wealth LLC500$30 03/31/2019
     QURE500$30 03/31/2019
Harvest Group Wealth Management LLC439$26 03/31/2019
     QURE439$26 03/31/2019
Bank of Montreal Can377$22 03/31/2019
     QURE377$22 03/31/2019
Quantamental Technologies LLC300$18 03/31/2019
     QURE300$18 03/31/2019
Daiwa Securities Group Inc.239$14 03/31/2019
     QURE239$14 03/31/2019
US Bancorp DE155$9 03/31/2019
     QURE155$9 03/31/2019
Ladenburg Thalmann Financial Services Inc.100$6 03/31/2019
     QURE100$6 03/31/2019
Resources Investment Advisors Inc.78$5 03/31/2019
     QURE78$5 03/31/2019
Proequities Inc. $4 03/31/2019
     QURE80$4 03/31/2019
     Put0$0 03/31/2019
     Call0$0 03/31/2019
Advisory Services Network LLC65$4 03/31/2019
     QURE65$4 03/31/2019
WealthBridge Capital Management LLC59$3 03/31/2019
     QURE59$3 03/31/2019
CenterStar Asset Management LLC $2 03/31/2019
     Call500$2 03/31/2019
Legacy Financial Advisors Inc.29$2 03/31/2019
     QURE29$2 03/31/2019
Northwestern Mutual Wealth Management Co.15$1 03/31/2019
     QURE15$1 03/31/2019
Clear Street Markets LLC $-2,345 06/30/2019
     Put300$2,345 06/30/2019
Point72 Asset Management L.P.100,000$-5,965 03/31/2019
     Put100,000$5,965 03/31/2019

See Summary: Institutional Holders of QURE
See Details: Top 10 Hedge Funds Holding QURE
Also See: QURE Holdings Changes

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Funds Holding QURE | www.HoldingsChannel.com

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