On this page, we present all of the funds holding PCVX from our database of 13F filers, detailed in the table below. The first column indicates the name of each of the funds holding PCVX, with a link to that fund's top holdings. The next columns indicate the amount of PCVX stock held by each of the funds holding PCVX, followed by the PCVX position size held by the fund, and lastly the date of the quarterly filing period the data represents. In total, we count 188 funds holding PCVX within the last two filing periods in our coverage universe of 13F filers, with the largest position size having been reported by FMR LLC. For more details on the positions held by FMR LLC (or by any of the other funds holding PCVX), click the fund name in the "Holder" column of the funds-holding-PCVX table below.

Holder	Amount	Position Size ($ in 1000's)	As of
FMR LLC	11,808,565	$442,585	03/31/2023
PCVX	11,808,565	$442,585	03/31/2023
RA Capital Management L.P.	7,291,254	$273,276	03/31/2023
PCVX	7,291,254	$273,276	03/31/2023
Janus Henderson Group PLC	7,127,611	$267,147	03/31/2023
PCVX	7,127,611	$267,147	03/31/2023
Vanguard Group Inc.	6,532,316	$244,831	03/31/2023
PCVX	6,532,316	$244,831	03/31/2023
BlackRock Inc.	5,081,865	$190,468	03/31/2023
PCVX	5,081,865	$190,468	03/31/2023
Wellington Management Group LLP	3,239,274	$121,408	03/31/2023
PCVX	3,239,274	$121,408	03/31/2023
State Street Corp	3,076,016	$115,289	03/31/2023
PCVX	3,076,016	$115,289	03/31/2023
Capital Research Global Investors	2,853,006	$106,931	03/31/2023
PCVX	2,853,006	$106,931	03/31/2023
Abingworth LLP	2,019,057	$96,814	12/31/2022
PCVX	2,019,057	$96,814	12/31/2022
Carlyle Group Inc.	1,923,158	$72,080	03/31/2023
PCVX	1,923,158	$72,080	03/31/2023
Medicxi Ventures Management Jersey Ltd	1,457,300	$54,620	03/31/2023
PCVX	1,457,300	$54,620	03/31/2023
Jennison Associates LLC	1,430,039	$53,598	03/31/2023
PCVX	1,430,039	$53,598	03/31/2023
Frazier Life Sciences Management L.P.	1,397,405	$52,375	03/31/2023
PCVX	1,397,405	$52,375	03/31/2023
Geode Capital Management LLC	1,329,339	$49,824	03/31/2023
PCVX	1,329,339	$49,824	03/31/2023
Braidwell LP	1,319,978	$49,473	03/31/2023
PCVX	1,319,978	$49,473	03/31/2023
Millennium Management LLC	1,313,642	$49,235	03/31/2023
PCVX	1,313,642	$49,235	03/31/2023
Kynam Capital Management LP	1,216,784	$45,605	03/31/2023
PCVX	1,216,784	$45,605	03/31/2023
TPG GP A LLC	1,190,336	$44,614	03/31/2023
PCVX	1,190,336	$44,614	03/31/2023
Perceptive Advisors LLC	1,170,000	$43,852	03/31/2023
PCVX	1,170,000	$43,852	03/31/2023
Citadel Advisors LLC		$32,174	03/31/2023
PCVX	854,110	$32,012	03/31/2023
Call	7,300	$274	03/31/2023
Put	3,000	$112	03/31/2023
Fred Alger Management LLC	844,778	$31,662	03/31/2023
PCVX	844,778	$31,662	03/31/2023
D. E. Shaw & Co. Inc.	794,907	$29,793	03/31/2023
PCVX	794,907	$29,793	03/31/2023
Novo Holdings A S	745,000	$27,923	03/31/2023
PCVX	745,000	$27,923	03/31/2023
T. Rowe Price Investment Management Inc.	733,907	$27,507	03/31/2023
PCVX	733,907	$27,507	03/31/2023
Orbimed Advisors LLC	729,439	$27,339	03/31/2023
PCVX	729,439	$27,339	03/31/2023
Franklin Resources Inc.	716,239	$26,845	03/31/2023
PCVX	716,239	$26,845	03/31/2023
Pivotal bioVenture Partners Investment Advisor LLC	693,039	$25,975	03/31/2023
PCVX	693,039	$25,975	03/31/2023
Pictet Asset Management SA	670,084	$25,115	03/31/2023
PCVX	670,084	$25,115	03/31/2023
Northern Trust Corp	668,302	$25,048	03/31/2023
PCVX	668,302	$25,048	03/31/2023
Great Point Partners LLC	659,211	$24,707	03/31/2023
PCVX	659,211	$24,707	03/31/2023
Driehaus Capital Management LLC	613,906	$23,009	03/31/2023
PCVX	613,906	$23,009	03/31/2023
Vivo Capital LLC	579,508	$21,720	03/31/2023
PCVX	579,508	$21,720	03/31/2023
Avidity Partners Management LP	510,000	$19,115	03/31/2023
PCVX	510,000	$19,115	03/31/2023
Point72 Asset Management L.P.	501,100	$18,781	03/31/2023
PCVX	501,100	$18,781	03/31/2023
Goldman Sachs Group Inc.	498,351	$18,678	03/31/2023
PCVX	498,351	$18,678	03/31/2023
Charles Schwab Investment Management Inc.	487,633	$18,276	03/31/2023
PCVX	487,633	$18,276	03/31/2023
Adage Capital Partners GP L.L.C.	435,000	$16,304	03/31/2023
PCVX	435,000	$16,304	03/31/2023
Nicholas Investment Partners LP	433,800	$16,259	03/31/2023
PCVX	433,800	$16,259	03/31/2023
Renaissance Technologies LLC	420,877	$15,774	03/31/2023
PCVX	420,877	$15,774	03/31/2023
Polar Asset Management Partners Inc.	413,300	$15,490	03/31/2023
PCVX	413,300	$15,490	03/31/2023
Victory Capital Management Inc.	393,249	$14,739	03/31/2023
PCVX	393,249	$14,739	03/31/2023
Soleus Capital Management L.P.	380,250	$14,252	03/31/2023
PCVX	380,250	$14,252	03/31/2023
Marshall Wace LLP	337,755	$12,659	03/31/2023
PCVX	337,755	$12,659	03/31/2023
Bank of New York Mellon Corp	301,046	$11,283	03/31/2023
PCVX	301,046	$11,283	03/31/2023
Tang Capital Management LLC	300,000	$11,244	03/31/2023
PCVX	300,000	$11,244	03/31/2023
Eversept Partners LP	299,050	$11,208	03/31/2023
PCVX	299,050	$11,208	03/31/2023
JPMorgan Chase & Co.		$11,187	03/31/2023
PCVX	292,896	$10,977	03/31/2023
Call	5,600	$210	03/31/2023
Deerfield Management Company L.P. Series C	295,000	$11,057	03/31/2023
PCVX	295,000	$11,057	03/31/2023
Bank of America Corp DE	284,109	$10,648	03/31/2023
PCVX	284,109	$10,648	03/31/2023
Dimensional Fund Advisors LP	278,043	$10,421	03/31/2023
PCVX	278,043	$10,421	03/31/2023
Cormorant Asset Management LP	275,000	$10,307	03/31/2023
PCVX	275,000	$10,307	03/31/2023
Nuveen Asset Management LLC	259,218	$9,715	03/31/2023
PCVX	259,218	$9,715	03/31/2023
Woodline Partners LP	250,000	$9,370	03/31/2023
PCVX	250,000	$9,370	03/31/2023
Ensign Peak Advisors Inc	248,886	$9,328	03/31/2023
PCVX	248,886	$9,328	03/31/2023
Two Sigma Investments LP	238,398	$8,935	03/31/2023
PCVX	238,398	$8,935	03/31/2023
Voloridge Investment Management LLC	235,581	$8,830	03/31/2023
PCVX	235,581	$8,830	03/31/2023
Eagle Asset Management Inc.	227,693	$8,533	03/31/2023
PCVX	227,693	$8,533	03/31/2023
Ghost Tree Capital LLC	225,000	$8,433	03/31/2023
PCVX	225,000	$8,433	03/31/2023
Ikarian Capital LLC	225,000	$8,433	03/31/2023
PCVX	225,000	$8,433	03/31/2023
Pier Capital LLC	202,560	$7,592	03/31/2023
PCVX	202,560	$7,592	03/31/2023
Commodore Capital LP	200,000	$7,496	03/31/2023
PCVX	200,000	$7,496	03/31/2023
Parkman Healthcare Partners LLC	186,097	$6,975	03/31/2023
PCVX	186,097	$6,975	03/31/2023
Rafferty Asset Management LLC	179,881	$6,742	03/31/2023
PCVX	179,881	$6,742	03/31/2023
Opaleye Management Inc.	177,000	$6,634	03/31/2023
PCVX	177,000	$6,634	03/31/2023
Morgan Stanley	170,623	$6,395	03/31/2023
PCVX	170,623	$6,395	03/31/2023
Citigroup Inc.	148,086	$5,550	03/31/2023
PCVX	148,086	$5,550	03/31/2023
Susquehanna International Group LLP		$5,438	03/31/2023
PCVX	90,605	$3,396	03/31/2023
Call	78,400	$2,938	03/31/2023
Put	23,900	$896	03/31/2023
Acuta Capital Partners LLC	120,500	$4,516	03/31/2023
PCVX	120,500	$4,516	03/31/2023
Swiss National Bank	119,300	$4,471	03/31/2023
PCVX	119,300	$4,471	03/31/2023
Jump Financial LLC	105,800	$3,965	03/31/2023
PCVX	105,800	$3,965	03/31/2023
Rhumbline Advisers	95,174	$3,567	03/31/2023
PCVX	95,174	$3,567	03/31/2023
Barclays PLC	92,205	$3,456	03/31/2023
PCVX	92,205	$3,456	03/31/2023
Schonfeld Strategic Advisors LLC	91,214	$3,419	03/31/2023
PCVX	91,214	$3,419	03/31/2023
Sphera Funds Management LTD.	90,000	$3,373	03/31/2023
PCVX	90,000	$3,373	03/31/2023
Walleye Capital LLC		$3,343	03/31/2023
PCVX	87,883	$3,294	03/31/2023
Call	1,300	$49	03/31/2023
Alliancebernstein L.P.	83,388	$3,125	03/31/2023
PCVX	83,388	$3,125	03/31/2023
Federated Hermes Inc.	76,913	$2,883	03/31/2023
PCVX	76,913	$2,883	03/31/2023
California State Teachers Retirement System	75,251	$2,820	03/31/2023
PCVX	75,251	$2,820	03/31/2023
Legal & General Group Plc	66,122	$2,478	03/31/2023
PCVX	66,122	$2,478	03/31/2023
Maven Securities LTD	65,000	$2,436	03/31/2023
PCVX	65,000	$2,436	03/31/2023
Affinity Asset Advisors LLC	62,223	$2,332	03/31/2023
PCVX	62,223	$2,332	03/31/2023
Sectoral Asset Management Inc	60,000	$2,249	03/31/2023
PCVX	60,000	$2,249	03/31/2023
UBS Asset Management Americas Inc.	56,031	$2,100	03/31/2023
PCVX	56,031	$2,100	03/31/2023
State of Wisconsin Investment Board	53,221	$1,995	03/31/2023
PCVX	53,221	$1,995	03/31/2023
Alps Advisors Inc.	52,726	$1,976	03/31/2023
PCVX	52,726	$1,976	03/31/2023
State of New Jersey Common Pension Fund D	52,723	$1,976	03/31/2023
PCVX	52,723	$1,976	03/31/2023
Wells Fargo & Company MN	51,906	$1,945	03/31/2023
PCVX	51,906	$1,945	03/31/2023
SG Americas Securities LLC	50,626	$1,897	03/31/2023
PCVX	50,626	$1,897	03/31/2023
Deutsche Bank AG	49,529	$1,856	03/31/2023
PCVX	49,529	$1,856	03/31/2023
Baker BROS. Advisors LP	48,885	$1,832	03/31/2023
PCVX	48,885	$1,832	03/31/2023
Credit Suisse AG	48,671	$1,824	03/31/2023
PCVX	48,671	$1,824	03/31/2023
New York State Common Retirement Fund	47,744	$1,789	03/31/2023
PCVX	47,744	$1,789	03/31/2023
Alyeska Investment Group L.P.	45,000	$1,687	03/31/2023
PCVX	45,000	$1,687	03/31/2023
Altium Capital Management LP	43,000	$1,612	03/31/2023
PCVX	43,000	$1,612	03/31/2023
Voya Investment Management LLC	42,789	$1,604	03/31/2023
PCVX	42,789	$1,604	03/31/2023
Prudential Financial Inc.	42,217	$1,582	03/31/2023
PCVX	42,217	$1,582	03/31/2023
Mirae Asset Global Investments Co. Ltd.	41,712	$1,563	03/31/2023
PCVX	41,712	$1,563	03/31/2023
Boothbay Fund Management LLC	40,677	$1,525	03/31/2023
PCVX	40,677	$1,525	03/31/2023
Two Sigma Advisers LP	39,500	$1,480	03/31/2023
PCVX	39,500	$1,480	03/31/2023
Invesco Ltd.	39,468	$1,479	03/31/2023
PCVX	39,468	$1,479	03/31/2023
Trexquant Investment LP	39,164	$1,468	03/31/2023
PCVX	39,164	$1,468	03/31/2023
Brown Brothers Harriman & Co.	38,033	$1,425	03/31/2023
PCVX	38,033	$1,425	03/31/2023
Tudor Investment Corp Et Al	37,861	$1,419	03/31/2023
PCVX	37,861	$1,419	03/31/2023
MetLife Investment Management LLC	37,576	$1,408	03/31/2023
PCVX	37,576	$1,408	03/31/2023
First Trust Advisors LP	37,210	$1,395	03/31/2023
PCVX	37,210	$1,395	03/31/2023
American International Group Inc.	34,613	$1,297	03/31/2023
PCVX	34,613	$1,297	03/31/2023
Profund Advisors LLC	34,086	$1,278	03/31/2023
PCVX	34,086	$1,278	03/31/2023
Price T Rowe Associates Inc. MD	32,028	$1,201	03/31/2023
PCVX	32,028	$1,201	03/31/2023
Jane Street Group LLC		$1,185	03/31/2023
PCVX	19,814	$743	03/31/2023
Call	11,800	$442	03/31/2023
Cubist Systematic Strategies LLC	30,308	$1,136	03/31/2023
PCVX	30,308	$1,136	03/31/2023
Neuberger Berman Group LLC	30,225	$1,133	03/31/2023
PCVX	30,225	$1,133	03/31/2023
The Manufacturers Life Insurance Company	28,960	$1,085	03/31/2023
PCVX	28,960	$1,085	03/31/2023
Man Group plc	25,492	$955	03/31/2023
PCVX	25,492	$955	03/31/2023
Squarepoint Ops LLC	25,169	$943	03/31/2023
PCVX	25,169	$943	03/31/2023
Guggenheim Capital LLC	24,389	$914	03/31/2023
PCVX	24,389	$914	03/31/2023
Renaissance Capital LLC	23,688	$888	03/31/2023
PCVX	23,688	$888	03/31/2023
Artia Global Partners LP	22,759	$853	03/31/2023
PCVX	22,759	$853	03/31/2023
Sei Investments Co.	21,827	$818	03/31/2023
PCVX	21,827	$818	03/31/2023
Algert Global LLC	21,837	$818	03/31/2023
PCVX	21,837	$818	03/31/2023
HRT Financial LP	21,688	$812	03/31/2023
PCVX	21,688	$812	03/31/2023
HighVista Strategies LLC	19,606	$735	03/31/2023
PCVX	19,606	$735	03/31/2023
DekaBank Deutsche Girozentrale	20,000	$722	03/31/2023
PCVX	20,000	$722	03/31/2023
TD Asset Management Inc.	19,200	$720	03/31/2023
PCVX	19,200	$720	03/31/2023
Teachers Retirement System of The State of Kentucky	18,970	$711	03/31/2023
PCVX	18,970	$711	03/31/2023
ETF Managers Group LLC	18,630	$698	03/31/2023
PCVX	18,630	$698	03/31/2023
Principal Financial Group Inc.	17,308	$649	03/31/2023
PCVX	17,308	$649	03/31/2023
State Board of Administration of Florida Retirement System	17,258	$647	03/31/2023
PCVX	17,258	$647	03/31/2023
Teacher Retirement System of Texas	17,032	$638	03/31/2023
PCVX	17,032	$638	03/31/2023
Parkwood LLC	16,955	$635	03/31/2023
PCVX	16,955	$635	03/31/2023
Arizona State Retirement System	16,019	$600	03/31/2023
PCVX	16,019	$600	03/31/2023
ProShare Advisors LLC	13,990	$524	03/31/2023
PCVX	13,990	$524	03/31/2023
Baker Avenue Asset Management LP	13,780	$516	03/31/2023
PCVX	13,780	$516	03/31/2023
Gilder Gagnon Howe & Co. LLC	13,568	$509	03/31/2023
PCVX	13,568	$509	03/31/2023
Public Employees Retirement Association of Colorado	13,412	$503	03/31/2023
PCVX	13,412	$503	03/31/2023
Caption Management LLC		$491	03/31/2023
Put	60,000	$2,249	03/31/2023
Call	60,000	$2,249	03/31/2023
PCVX	13,110	$491	03/31/2023
AQR Capital Management LLC	12,743	$478	03/31/2023
PCVX	12,743	$478	03/31/2023
Candriam Luxembourg S.C.A.	12,070	$416	03/31/2023
PCVX	12,070	$416	03/31/2023
Handelsbanken Fonder AB	10,300	$386	03/31/2023
PCVX	10,300	$386	03/31/2023
E Fund Management Co. Ltd.	10,212	$383	03/31/2023
PCVX	10,212	$383	03/31/2023
Amalgamated Bank	10,173	$381	03/31/2023
PCVX	10,173	$381	03/31/2023
Envestnet Asset Management Inc.	9,883	$370	03/31/2023
PCVX	9,883	$370	03/31/2023
Alpha Paradigm Partners LLC	7,665	$368	12/31/2022
PCVX	7,665	$368	12/31/2022
XTX Topco Ltd	9,729	$365	03/31/2023
PCVX	9,729	$365	03/31/2023
Seven Eight Capital LP	9,636	$361	03/31/2023
PCVX	9,636	$361	03/31/2023
J. Goldman & Co LP	8,821	$331	03/31/2023
PCVX	8,821	$331	03/31/2023
Chicago Partners Investment Group LLC	7,159	$311	03/31/2023
PCVX	7,159	$311	03/31/2023
Zurcher Kantonalbank Zurich Cantonalbank	8,212	$308	03/31/2023
PCVX	8,212	$308	03/31/2023
UBS Oconnor LLC	8,071	$303	03/31/2023
PCVX	8,071	$303	03/31/2023
Raymond James & Associates	7,600	$285	03/31/2023
PCVX	7,600	$285	03/31/2023
Fox Run Management L.L.C.	6,768	$254	03/31/2023
PCVX	6,768	$254	03/31/2023
Legato Capital Management LLC	6,525	$245	03/31/2023
PCVX	6,525	$245	03/31/2023
Ameritas Investment Partners Inc.	5,739	$215	03/31/2023
PCVX	5,739	$215	03/31/2023
Tekla Capital Management LLC	5,000	$187	03/31/2023
PCVX	5,000	$187	03/31/2023
Royal Bank of Canada	4,241	$159	03/31/2023
PCVX	4,241	$159	03/31/2023
Metropolitan Life Insurance Co NY	3,978	$149	03/31/2023
PCVX	3,978	$149	03/31/2023
Strs Ohio	4,000	$149	03/31/2023
PCVX	4,000	$149	03/31/2023
Allspring Global Investments Holdings LLC	3,469	$130	03/31/2023
PCVX	3,469	$130	03/31/2023
Virtus Investment Advisers Inc.	3,178	$119	03/31/2023
PCVX	3,178	$119	03/31/2023
Group One Trading L.P.		$116	03/31/2023
Call	5,800	$217	03/31/2023
Put	2,700	$101	03/31/2023
Great West Life Assurance Co. Can	2,658	$100	03/31/2023
PCVX	2,658	$100	03/31/2023
Tower Research Capital LLC TRC	2,497	$94	03/31/2023
PCVX	2,497	$94	03/31/2023
Advisor Group Holdings Inc.	2,547	$94	03/31/2023
PCVX	2,547	$94	03/31/2023
Cutler Group LP		$90	03/31/2023
PCVX	3,000	$112	03/31/2023
Put	3,000	$22	03/31/2023
Call	3,000	$0	03/31/2023
Virtus ETF Advisers LLC	2,211	$83	03/31/2023
PCVX	2,211	$83	03/31/2023
Nisa Investment Advisors LLC	1,712	$64	03/31/2023
PCVX	1,712	$64	03/31/2023
Manchester Capital Management LLC	1,500	$56	03/31/2023
PCVX	1,500	$56	03/31/2023
China Universal Asset Management Co. Ltd.	1,084	$41	03/31/2023
PCVX	1,084	$41	03/31/2023
US Bancorp DE	854	$32	03/31/2023
PCVX	854	$32	03/31/2023
Russell Investments Group Ltd.	805	$30	03/31/2023
PCVX	805	$30	03/31/2023
Point72 Middle East FZE	694	$26	03/31/2023
PCVX	694	$26	03/31/2023
UBS Group AG	344	$13	03/31/2023
PCVX	344	$13	03/31/2023
Daiwa Securities Group Inc.	318	$12	03/31/2023
PCVX	318	$12	03/31/2023
Lindbrook Capital LLC	327	$12	03/31/2023
PCVX	327	$12	03/31/2023
TCI Wealth Advisors Inc.	258	$10	03/31/2023
PCVX	258	$10	03/31/2023
Signaturefd LLC	201	$8	03/31/2023
PCVX	201	$8	03/31/2023
Ronald Blue Trust Inc.	156	$7	03/31/2023
PCVX	156	$7	03/31/2023
Belpointe Asset Management LLC	148	$6	03/31/2023
PCVX	148	$6	03/31/2023
The PNC Financial Services Group Inc.	117	$4	03/31/2023
PCVX	117	$4	03/31/2023
Ellevest Inc.	45	$2	03/31/2023
PCVX	45	$2	03/31/2023
First Horizon Advisors Inc.	35	$1	03/31/2023
PCVX	35	$1	03/31/2023
Parallel Advisors LLC	21	$1	03/31/2023
PCVX	21	$1	03/31/2023
Harvest Group Wealth Management LLC	14	$1	03/31/2023
PCVX	14	$1	03/31/2023
Washington Trust Advisors Inc.	32	$1	03/31/2023
PCVX	32	$1	03/31/2023
Proequities Inc.		$0	03/31/2023
Put	0	$0	03/31/2023
Call	0	$0	03/31/2023
PCVX	0	$0	03/31/2023
Nomura Asset Management Co. Ltd.	0	$0	03/31/2023
PCVX	0	$0	03/31/2023
CWM LLC	9	$0	03/31/2023
PCVX	9	$0	03/31/2023
Institutional & Family Asset Management LLC	8	$0	03/31/2023
PCVX	8	$0	03/31/2023
Bell Investment Advisors Inc	13	$0	03/31/2023
PCVX	13	$0	03/31/2023
Covestor Ltd	6	$0	03/31/2023
PCVX	6	$0	03/31/2023

See Summary: Institutional Holders of PCVX
See Details: Top 10 Hedge Funds Holding PCVX
Also See: PCVX Insider Buying
Also See: PCVX Holdings Changes

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