All Stocks Held By Orbimed Advisors LLC

As of 12/31/2023, we find all stocks held by Orbimed Advisors LLC to be as follows, presented in the table below with each row detailing each Orbimed Advisors LLC position, ordered by largest to smallest position size. The all-stocks-held-by-Orbimed Advisors LLC table shows the entity held in the first column (click any entity to explore other funds holding positions), the share amount held, the share count change between the last two reporting periods, and finally the position size for all stocks held by Orbimed Advisors LLC as of the latest filing.

Entity	Amount	Change 09/30/2023 to 12/31/2023	Position Size ($ in 1000's)
BIOGEN INC	827,600	+270,800	$214,158
BIIB	827,600	+270,800	$214,158
ELI LILLY & CO	365,400	+179,400	$212,999
LLY	365,400	+179,400	$212,999
BOSTON SCIENTIFIC CORP	3,306,800	UNCH	$191,166
BSX	3,306,800	UNCH	$191,166
INTUITIVE SURGICAL INC	499,000	UNCH	$168,343
ISRG	499,000	UNCH	$168,343
EDGEWISE THERAPEUTICS INC	14,567,176	UNCH	$159,365
EWTX	14,567,176	UNCH	$159,365
BIOMARIN PHARMACEUTICAL INC	1,571,410	-43,800	$151,515
BMRN	1,571,410	-43,800	$151,515
RAYZEBIO INC	2,365,213	-257,696	$147,045
RYZB	2,365,213	-257,696	$147,045
ENLIVEN THERAPEUTICS INC	8,998,338	UNCH	$124,537
ELVN	8,998,338	UNCH	$124,537
SPRINGWORKS THERAPEUTICS INC	3,219,359	-749,229	$117,507
SWTX	3,219,359	-749,229	$117,507
MERCK & CO INC	1,055,000	UNCH	$115,016
MRK	1,055,000	UNCH	$115,016
IONIS PHARMACEUTICALS INC	2,064,797	-104,703	$104,458
IONS	2,064,797	-104,703	$104,458
DISC MEDICINE INC	1,702,237	-567,400	$98,321
IRON	1,702,237	-567,400	$98,321
GRACELL BIOTECHNOLOGIES INC	9,308,726	UNCH	$93,460
GRCL	9,308,726	UNCH	$93,460
TENET HEALTHCARE CORP	1,224,400	UNCH	$92,528
THC	1,224,400	UNCH	$92,528
EVOLENT HEALTH INC	2,746,532	-149,100	$90,718
EVH	2,746,532	-149,100	$90,718
UNITED THERAPEUTICS CORP DEL	386,100	-15,800	$84,900
UTHR	386,100	-15,800	$84,900
XTANT MED HLDGS INC	73,114,592	UNCH	$82,619
XTNT	73,114,592	UNCH	$82,619
STRYKER CORPORATION	269,000	UNCH	$80,555
SYK	269,000	UNCH	$80,555
SCHOLAR ROCK HLDG CORP	4,245,000	+2,211,211	$79,806
SRRK	4,245,000	+2,211,211	$79,806
THERMO FISHER SCIENTIFIC INC	143,800	UNCH	$76,328
TMO	143,800	UNCH	$76,328
VERONA PHARMA PLC	3,777,778	UNCH	$75,102
VRNA	3,777,778	UNCH	$75,102
VAXCYTE INC	1,153,091	+145,943	$72,414
PCVX	1,153,091	+145,943	$72,414
THESEUS PHARMACEUTICALS INC	17,713,600	UNCH	$71,740
THRX	17,713,600	UNCH	$71,740
VERTEX PHARMACEUTICALS INC	175,200	+9,800	$71,287
VRTX	175,200	+9,800	$71,287
PRELUDE THERAPEUTICS INC			$70,837
PRLD	10,909,256	UNCH	$46,583
NONVOTING	5,680,186	UNCH	$24,254
NEUROCRINE BIOSCIENCES INC	519,279	+103,379	$68,420
NBIX	519,279	+103,379	$68,420
SAREPTA THERAPEUTICS INC	697,500	+168,300	$67,260
SRPT	697,500	+168,300	$67,260
ELEVANCE HEALTH INC	141,500	+141,500	$66,726
ELV	141,500	+141,500	$66,726
THIRD HARMONIC BIO INC	5,779,071	UNCH	$63,396
THRD	5,779,071	UNCH	$63,396
NATERA INC	954,481	+33,900	$59,789
NTRA	954,481	+33,900	$59,789
CRINETICS PHARMACEUTICALS IN	1,667,360	-1,228,714	$59,325
CRNX	1,667,360	-1,228,714	$59,325
APELLIS PHARMACEUTICALS INC	922,200	-415,800	$55,203
APLS	922,200	-338,300	$55,203
R1 RCM INC	4,803,200	+1,362,200	$50,770
RCM	4,803,200	+1,362,200	$50,770
ARS PHARMACEUTICALS INC	9,240,887	UNCH	$50,640
SPRY	9,240,887	UNCH	$50,640
KEROS THERAPEUTICS INC	1,268,734	-246,000	$50,445
KROS	1,268,734	-246,000	$50,445
HUMANA INC	109,900	-232,600	$50,313
HUM	109,900	-232,600	$50,313
TERNS PHARMACEUTICALS INC	7,619,135	UNCH	$49,448
TERN	7,619,135	UNCH	$49,448
ALPINE IMMUNE SCIENCES INC	2,535,245	-1,546,347	$48,322
ALPN	2,535,245	-1,546,347	$48,322
SI BONE INC	2,292,531	UNCH	$48,120
SIBN	2,292,531	UNCH	$48,120
ALX ONCOLOGY HLDGS INC	3,095,000	+224,000	$46,085
ALXO	3,095,000	+224,000	$46,085
NEUROPACE INC	4,003,967	-8,314	$41,281
NPCE	4,003,967	-8,314	$41,281
IOVANCE BIOTHERAPEUTICS INC	4,707,458	UNCH	$38,272
IOVA	4,707,458	UNCH	$38,272
SYNDAX PHARMACEUTICALS INC	1,749,000	+465,000	$37,796
SNDX	1,749,000	+465,000	$37,796
ICON PLC	132,200	UNCH	$37,422
ICLR	132,200	UNCH	$37,422
UNITEDHEALTH GROUP INC	70,000	UNCH	$36,853
UNH	70,000	UNCH	$36,853
AMGEN INC	127,300	UNCH	$36,665
AMGN	127,300	UNCH	$36,665
APOGEE THERAPEUTICS INC	1,277,901	-150,000	$35,705
APGE	1,277,901	-150,000	$35,705
JANUX THERAPEUTICS INC	3,317,927	UNCH	$35,601
JANX	3,317,927	UNCH	$35,601
COMPASS THERAPEUTICS INC	22,362,850	UNCH	$34,886
CMPX	22,362,850	UNCH	$34,886
SCPHARMACEUTICALS INC	5,559,528	UNCH	$34,858
SCPH	5,559,528	UNCH	$34,858
ARGENX SE	84,600	+52,000	$32,184
ARGX	84,600	+52,000	$32,184
FUSION PHARMACEUTICALS INC	3,122,770	UNCH	$30,010
FUSN	3,122,770	UNCH	$30,010
ACELYRIN INC	4,001,711	-1,324,591	$29,853
SLRN	4,001,711	-1,324,591	$29,853
NEUMORA THERAPEUTICS INC.	1,500,000	UNCH	$25,575
NMRA	1,500,000	UNCH	$25,575
XENON PHARMACEUTICALS INC	550,000	-408,793	$25,333
XENE	550,000	-408,793	$25,333
RHYTHM PHARMACEUTICALS INC	536,642	-47,000	$24,669
RYTM	536,642	-47,000	$24,669
REPARE THERAPEUTICS INC	3,322,488	UNCH	$24,254
RPTX	3,322,488	UNCH	$24,254
ABCELLERA BIOLOGICS INC	4,180,768	UNCH	$23,872
ABCL	4,180,768	UNCH	$23,872
VERA THERAPEUTICS INC	1,518,115	UNCH	$23,349
VERA	1,518,115	UNCH	$23,349
PMV PHARMACEUTICALS INC	6,475,291	-87,786	$20,073
PMVP	6,475,291	-87,786	$20,073
IKENA ONCOLOGY INC			$19,519
NONVOTING	6,368,587	UNCH	$12,546
IKNA	3,539,358	+353,192	$6,973
KINNATE BIOPHARMA INC	8,009,729	UNCH	$18,983
KNTE	8,009,729	UNCH	$18,983
TELA BIO INC	2,835,542	UNCH	$18,771
TELA	2,835,542	UNCH	$18,771
SINOVAC BIOTECH LTD	2,718,735	UNCH	$17,590
SVA	2,718,735	UNCH	$17,590
AEROVATE THERAPEUTICS INC	756,930	UNCH	$17,129
AVTE	756,930	UNCH	$17,129
INVIVYD INC	4,127,565	-1,142,835	$16,263
IVVD	4,127,565	-1,142,835	$16,263
IMMATICS N.V	1,543,407	+368,207	$16,252
IMTX	1,543,407	+493,207	$16,252
ADICET BIO INC	8,322,140	UNCH	$15,729
ACET	8,322,140	UNCH	$15,729
ALNYLAM PHARMACEUTICALS INC	79,400	+79,400	$15,198
ALNY	79,400	+79,400	$15,198
PFIZER INC			$14,395
Call	500,000	+500,000	$14,395
KRYSTAL BIOTECH INC	103,700	+103,700	$12,865
KRYS	103,700	+103,700	$12,865
VERASTEM INC	1,529,115	UNCH	$12,447
VSTM	1,529,115	UNCH	$12,447
CORVUS PHARMACEUTICALS INC	6,943,654	UNCH	$12,221
CRVS	6,943,654	UNCH	$12,221
REGENERON PHARMACEUTICALS	13,500	UNCH	$11,857
REGN	13,500	UNCH	$11,857
AMICUS THERAPEUTICS INC	806,000	+806,000	$11,437
FOLD	806,000	+806,000	$11,437
PASSAGE BIO INC	10,124,576	UNCH	$10,226
PASG	10,124,576	UNCH	$10,226
HERON THERAPEUTICS INC	5,928,591	+5,125,891	$10,079
HRTX	5,928,591	+5,125,891	$10,079
ARROWHEAD PHARMACEUTICALS IN	319,651	-114,000	$9,781
ARWR	319,651	-114,000	$9,781
UNIQURE NV	1,347,900	-716,555	$9,125
QURE	1,347,900	-716,555	$9,125
DEXCOM INC	73,200	+23,200	$9,083
DXCM	73,200	+73,200	$9,083
APOLLOMICS INC	8,565,456	-9,428,179	$8,266
APLM	8,565,456	-9,428,179	$8,266
GILEAD SCIENCES INC	100,000	UNCH	$8,101
GILD	100,000	UNCH	$8,101
MORPHIC HLDG INC	273,400	+64,900	$7,896
MORF	273,400	+64,900	$7,896
TURNSTONE BIOLOGICS CORP	3,099,265	UNCH	$7,888
TSBX	3,099,265	UNCH	$7,888
RAPT THERAPEUTICS INC	281,413	-963,532	$6,993
RAPT	281,413	-963,532	$6,993
INSPIREMD INC	2,133,405	+273,000	$5,995
NSPR	2,133,405	+273,000	$5,995
X4 PHARMACEUTICALS INC	7,133,515	UNCH	$5,981
XFOR	7,133,515	UNCH	$5,981
CULLINAN ONCOLOGY INC	544,848	UNCH	$5,552
CGEM	544,848	UNCH	$5,552
ORIC PHARMACEUTICALS INC	522,968	-370,700	$4,811
ORIC	522,968	-370,700	$4,811
ILLUMINA INC	30,300	+30,300	$4,219
ILMN	30,300	+30,300	$4,219
AMBRX BIOPHARMA INC	296,000	+296,000	$4,215
AMAM	296,000	+296,000	$4,215
NEXTCURE INC	2,711,013	UNCH	$3,091
NXTC	2,711,013	UNCH	$3,091
CELLDEX THERAPEUTICS INC NEW	58,800	+58,800	$2,332
CLDX	58,800	+58,800	$2,332
ARCUS BIOSCIENCES INC	117,000	+117,000	$2,235
RCUS	117,000	+117,000	$2,235
10X GENOMICS INC	39,800	+39,800	$2,227
TXG	39,800	+39,800	$2,227
FATE THERAPEUTICS INC	528,080	+528,080	$1,975
FATE	528,080	+528,080	$1,975
KEZAR LIFE SCIENCES INC	1,927,000	-3,536,000	$1,826
KZR	1,927,000	-3,536,000	$1,826
BOLT BIOTHERAPEUTICS INC	1,541,000	UNCH	$1,726
BOLT	1,541,000	UNCH	$1,726
YS BIOPHARMA CO LTD	3,236,311	-1,305,111	$1,654
YS	3,236,311	-1,305,111	$1,654
VIGIL NEUROSCIENCE INC	448,891	UNCH	$1,517
VIGL	448,891	UNCH	$1,517
BIOMX INC	4,517,589	-35,900	$1,265
PHGE	4,517,589	-35,900	$1,265
CHEMOMAB THERAPEUTICS LTD	2,241,274	UNCH	$1,143
CMMB	2,241,274	UNCH	$1,143
GERON CORP	485,000	+485,000	$1,023
GERN	485,000	+485,000	$1,023
VIR BIOTECHNOLOGY INC	101,000	+101,000	$1,016
VIR	101,000	+101,000	$1,016
AGIOS PHARMACEUTICALS INC	45,000	+45,000	$1,002
AGIO	45,000	+45,000	$1,002
CALCIMEDICA INC	297,380	UNCH	$851
CALC	297,380	UNCH	$851
ELEVATION ONCOLOGY INC	1,500,000	UNCH	$806
ELEV	1,500,000	UNCH	$806
ACUTUS MED INC	2,648,386	UNCH	$535
AFIB	2,648,386	UNCH	$535
SINGULAR GENOMICS SYSTEMS IN	540,697	+0	$249
OMIC	540,697	UNCH	$249
ABBVIE INC			$0 (exited)
ABBV	0	-330,000	$0
AKERO THERAPEUTICS INC			$0 (exited)
AKRO	0	-350,000	$0
ALTIMMUNE INC			$0 (exited)
ALT	0	-100,000	$0
ARCUTIS BIOTHERAPEUTICS INC			$0 (exited)
ARQT	0	-1,914,479	$0
ASTRAZENECA PLC			$0 (exited)
Call	0	-250,000	$0
BAXTER INTL INC			$0 (exited)
BAX	0	-2,239,900	$0
BIOATLA INC			$0 (exited)
BCAB	0	-1,009,279	$0
THE CIGNA GROUP			$0 (exited)
CI	0	-231,500	$0
CUTERA INC			$0 (exited)
CUTR	0	-603,100	$0
ESSA PHARMA INC			$0 (exited)
EPIX	0	-842,366	$0
GOODRX HLDGS INC			$0 (exited)
GDRX	0	-1,595,000	$0
GALECTO INC			$0 (exited)
GLTO	0	-924,788	$0
HARPOON THERAPEUTICS INC			$0 (exited)
HARP	0	-62,121	$0
HORIZON THERAPEUTICS PUB L			$0 (exited)
HZNP	0	-266,400	$0
KARUNA THERAPEUTICS INC			$0 (exited)
KRTX	0	-14,000	$0
KENVUE INC			$0 (exited)
KVUE	0	-312,404	$0
Call	0	-250,000	$0
MADRIGAL PHARMACEUTICALS INC			$0 (exited)
MDGL	0	-253,309	$0
MOONLAKE IMMUNOTHERAPEUTICS			$0 (exited)
MLTX	0	-117,000	$0
MIRATI THERAPEUTICS INC			$0 (exited)
MRTX	0	-1,959,050	$0
Call	0	-100,000	$0
RELAY THERAPEUTICS INC			$0 (exited)
RLAY	0	-501,966	$0
SEAGEN INC			$0 (exited)
Call	0	-50,000	$0
SGEN	0	-42,600	$0
SYNLOGIC INC			$0 (exited)
SYBX	0	-401,998	$0
PROTARA THERAPEUTICS INC			$0 (exited)
TARA	0	-772,584	$0
TELADOC HEALTH INC			$0 (exited)
TDOC	0	-110,000	$0
VENTYX BIOSCIENCES INC			$0 (exited)
VTYX	0	-340,384	$0
XENCOR INC	0	-19,142	$0 (exited)
XNCR	0	-19,142	$0

See Summary: Orbimed Advisors LLC Top Holdings
See Details: Top 10 Stocks Held By Orbimed Advisors LLC

Entity	Shares/Amount Change	Position Value Change
Biggest New Positions
ELV	+141,500	+$66,726
ALNY	+79,400	+$15,198
PFE	+500,000	+$14,395
KRYS	+103,700	+$12,865
FOLD	+806,000	+$11,437
ILMN	+30,300	+$4,219
AMAM	+296,000	+$4,215
CLDX	+58,800	+$2,332
RCUS	+117,000	+$2,235
TXG	+39,800	+$2,227

Entity	Shares/Amount Change	Position Value Change
Biggest Exited Positions
MRTX	-2,059,050	-$89,692
BAX	-2,239,900	-$84,534
CI	-231,500	-$66,225
ABBV	-330,000	-$49,190
MDGL	-253,309	-$36,993
HZNP	-266,400	-$30,820
SGEN	-92,600	-$19,646
AKRO	-350,000	-$17,703
AZN	-250,000	-$16,930
VTYX	-340,384	-$11,822

Entity	Shares/Amount Change	Position Value Change
Biggest Position Increases
HRTX	+5,125,891	+$9,252
SRRK	+2,211,211	+$65,366
RCM	+1,362,200	-$1,086
SNDX	+465,000	+$19,152
IMTX	+368,207	+$2,643
IKNA	+353,192	-$21,853
NSPR	+273,000	-$89
BIIB	+270,800	+$71,055
ALXO	+224,000	+$32,304
LLY	+179,400	+$113,093

Entity	Shares/Amount Change	Position Value Change
Biggest Position Decreases
APLM	-9,428,179	-$59,120
KZR	-3,536,000	-$4,675
ALPN	-1,546,347	+$1,588
SLRN	-1,324,591	-$24,315
YS	-1,305,111	-$1,979
CRNX	-1,228,714	-$26,804
IVVD	-1,142,835	+$7,303
RAPT	-963,532	-$13,698
SWTX	-749,229	+$25,753

Orbimed Advisors LLC Info

Size ($ in 1000's)
At 12/31/2023: $4,684,837
At 09/30/2023: $4,385,161

Combined Holding Report Includes:
ORBIMED ADVISORS LLC
ORBIMED CAPITAL LLC

Orbimed Advisors LLC holdings changes, total fund size, and other information presented on HoldingsChannel.com was derived from Orbimed Advisors LLC 13F filings. Link to 13F filings: SEC filings

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