HoldingsChannel.com
Sphera Funds Management LTD. Top Holdings
As of  12/31/2022, below is a summary of the Sphera Funds Management LTD. top holdings by largest position size, as per the latest 13f filing made by Sphera Funds Management LTD.. In the Sphera Funds Management LTD.-top-holdings-table below, each of the top holdings by name is presented in the first column, followed by the amount of shares held by Sphera Funds Management LTD. in that top holding, then the share count change between reporting periods, and finally the Sphera Funds Management LTD. top holding position size for that row.

   EntityAmountChange
 09/30/2022 to 12/31/2022
Position Size
($ in 1000's)
ASTRAZENECA PLC 400,060 -497,000 $27,124
     AZN400,060-497,000$27,124
SANOFI 559,515 -655,000 $27,097
     SNY559,515-655,000$27,097
TEVA PHARMACEUTICAL INDS LTD      $20,267
     Call2,222,300+12,300$20,267
JOHNSON & JOHNSON 109,831 -106,320 $19,402
     JNJ109,831-106,320$19,402
SYNDAX PHARMACEUTICALS INC 710,561 -112,135 $18,084
     SNDX710,561-112,135$18,084
MERCK & CO INC 120,600 -246,400 $13,381
     MRK120,600-246,400$13,381
CRINETICS PHARMACEUTICALS IN 671,644 +45,092 $12,291
     CRNX671,644+45,092$12,291
ALBIREO PHARMA INC 463,828 +104,828 $10,023
     ALBO463,828+104,828$10,023
ABBVIE INC 60,000 -102,285 $9,697
     ABBV60,000-102,285$9,697
NOVO NORDISK A S 71,540 -224,900 $9,682
     NVO71,540-224,900$9,682
LILLY ELI & CO 25,690 -117,860 $9,398
     LLY25,690-117,860$9,398
KEZAR LIFE SCIENCES INC 1,305,183 +59,377 $9,188
     KZR1,305,183+59,377$9,188
ULTRAGENYX PHARMACEUTICAL IN 183,696 +10,000 $8,511
     RARE183,696+10,000$8,511
SPRINGWORKS THERAPEUTICS INC 316,625 +15,000 $8,235
     SWTX316,625+15,000$8,235
KEROS THERAPEUTICS INC 158,757 -48,062 $7,624
     KROS158,757-48,062$7,624
ARCELLX INC 237,488 -96,592 $7,357
     ACLX237,488-96,592$7,357
ASTRIA THERAPEUTICS INC 469,340 +469,340 $6,988
     ATXS469,340+469,340$6,988
POINT BIOPHARMA GLOBAL INC 952,642 -100,200 $6,945
     PNT952,642-100,200$6,945
KURA ONCOLOGY INC 558,287 -231,665 $6,928
     KURA558,287-231,665$6,928
IMMATICS N.V 780,852 -14,554 $6,801
     IMTX780,852-14,554$6,801
CINCOR PHARMA INC 529,640 +410,690 $6,509
     CINC529,640+410,690$6,509
FIVE9 INC 95,000 +95,000 $6,447
     FIVN95,000+95,000$6,447
ALTIMMUNE INC 380,298 -120,000 $6,256
     ALT380,298-220,000$6,256
CONCERT PHARMACEUTICALS INC 1,002,783 +50,000 $5,856
     CNCE1,002,783+50,000$5,856
SPDR SER TR (XBI) 70,000 +70,000 $5,810
     XBI70,000+70,000$5,810
INVESCO QQQ TR      $5,592
     Call231,000+231,000$61,511
     Put210,000-115,500$55,919
GENERAC HLDGS INC 50,000 +14,400 $5,033
     GNRC50,000+50,000$5,033
MERUS N V 316,993 +3,667 $4,904
     MRUS316,993+3,667$4,904
KINIKSA PHARMACEUTICALS LTD 307,283 +307,283 $4,603
     KNSA307,283+307,283$4,603
LEONARDO DRS INC 335,557 +335,557 $4,288
     DRS335,557+335,557$4,288
IVERIC BIO INC 195,591 -386,238 $4,188
     ISEE195,591-386,238$4,188
BELLUS HEALTH INC NEW 489,860 +25,000 $4,027
     BLU489,860+25,000$4,027
FIVERR INTL LTD      $4,014
     NOTE 11 04,951,000UNCH$4,014
RIGEL PHARMACEUTICALS INC 2,278,845 +116,259 $3,418
     RIGL2,278,845+116,259$3,418
CHINOOK THERAPEUTICS INC 127,200 -407,158 $3,333
     KDNY127,200-407,158$3,333
CAMTEK LTD 110,000 +110,000 $2,416
     CAMT110,000+110,000$2,416
REZOLUTE INC 1,155,897 UNCH $2,393
     RZLT1,155,897UNCH$2,393
89BIO INC      $2,345
     ETNB180,600-478,184$2,299
     Call3,600+3,600$46
BIOGEN INC 7,516 -47,984 $2,081
     BIIB7,516-47,984$2,081
STOKE THERAPEUTICS INC 188,640 +31,440 $1,741
     STOK188,640+31,440$1,741
INOZYME PHARMA INC 1,625,058 +450,000 $1,706
     INZY1,625,058+450,000$1,706
PMV PHARMACEUTICALS INC 187,800 UNCH $1,634
     PMVP187,800UNCH$1,634
BIOATLA INC 186,600 +186,600 $1,539
     BCAB186,600+186,600$1,539
ALPINE IMMUNE SCIENCES INC 200,000 UNCH $1,470
     ALPN200,000UNCH$1,470
WEREWOLF THERAPEUTICS INC 626,810 UNCH $1,285
     HOWL626,810UNCH$1,285
MEDIWOUND LTD 75,413 -613,303 $1,017
     MDWD75,413-613,303$1,017
AUTOLUS THERAPEUTICS PLC 500,000 +500,000 $950
     AUTL500,000+500,000$950
APPLIED MATLS INC 8,499 +8,499 $828
     AMAT8,499+8,499$828
INFINITY PHARMACEUTICALS INC 1,476,000 UNCH $819
     INFI1,476,000UNCH$819
NICE SYS INC      $577
     NOTE 1250,000UNCH$577

See Full List: All Stocks Held By Sphera Funds Management LTD.
— Including:
     • Biggest new positions
     • Biggest exits
     • Biggest increased positions
     • Biggest decreased positions

See Details: Top 10 Stocks Held By Sphera Funds Management LTD.

Size ($ in 1000's)
At 12/31/2022: $465,932
At 09/30/2022: $720,456

Combined Holding Report Includes:
SPHERA FUNDS MANAGEMENT LTD.
Sphera Global Healthcare Management LP
Sphera Global Healthcare GP Ltd.

Sphera Funds Management LTD. holdings changes, total fund size, and other information presented on HoldingsChannel.com was derived from Sphera Funds Management LTD. 13F filings. Link to 13F filings: SEC filings

Sphera Funds Management LTD. Top Holdings 13F Filings | www.HoldingsChannel.com

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